ENSDARG00000055750


Danio rerio

Features
Gene ID: ENSDARG00000055750
  
Biological name :foxp3a
  
Synonyms : forkhead box P3a / foxp3a
  
Possible biological names infered from orthology : forkhead box P3 / Forkhead box protein P3 Forkhead box protein P3, C-terminally processed Forkhead box protein P3 41 kDa form / FOXP3 / Q99JB6 / Q9BZS1
  
Species: Danio rerio
  
Chr. number: 8
Strand: -1
Band:
Gene start: 25716308
Gene end: 25729543
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000072611
Ensembl peptide - ENSDARP00000108584
Ensembl peptide - ENSDARP00000080214
NCBI entrez gene - 571165     See in Manteia.
RefSeq - NM_001329567
RefSeq - XM_021478298
RefSeq Peptide - NP_001316496
swissprot - A1L5C8
swissprot - D2EAB6
swissprot - A8WFW7
ZFIN ID - ZDB-GENE-061116-2
Ensembl - ENSDARG00000055750
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 FOXP3ENSG00000049768Homo sapiens
 Foxp3ENSMUSG00000039521Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
foxp2 / forkhead box P2ENSDARG0000000545337
foxp1b / forkhead box P1b / Foxp1* / P58462* / Mus musculus forkhead box P1 (Foxp1), transcript variant 4, mRNA.*ENSDARG0000001418136
foxp4 / forkhead box P4ENSDARG0000007612035
foxp1a / forkhead box P1aENSDARG0000000484334
foxp3b / forkhead box P3b / FOXP3* / Q99JB6* / Q9BZS1* / forkhead box P3* / Forkhead box protein P3 Forkhead box protein P3, C-terminally processed Forkhead box protein P3 41 kDa form*ENSDARG0000007827930
foxd3 / forkhead box D3 / FOXD4* / Q9UJU5* / Q12950* / Q3SYB3* / Q5VV16* / Q60688* / Q6VB84* / Q8WXT5* / Q9NU39* / FOXD4L3* / FOXD4L4* / FOXD4L5* / FOXD4L6* / FOXD4L1* / forkhead box D4* / ...ENSDARG0000002103212
foxg1a / forkhead box G1a / FOXG1* / P55316* / Q60987* / Gm43517* / forkhead box G1* / Forkhead box protein G1 *ENSDARG0000007076912
foxf1 / A1L1S5 / forkhead box F1 / Q61080* / Q12946* / Forkhead box protein F1 *ENSDARG0000001539912
foxd2 / forkhead box D2 / FOXD1* / O35392* / O60548* / Q16676* / Q61345* / forkhead box D1* / Forkhead box protein D1 * / Forkhead box protein D2 *ENSDARG0000005813312
foxf2b / forkhead box F2b / FOXF2* / O54743* / Q12947* / forkhead box F2* / Forkhead box protein F2 *ENSDARG0000007038912
foxf2a / forkhead box F2a / FOXF2* / O54743* / Q12947* / forkhead box F2* / Forkhead box protein F2 *ENSDARG0000001719511
foxe3 / forkhead box E3 / FOXE1* / O00358* / Q13461* / Q8R2I0* / Q9QY14* / forkhead box E1* / Forkhead box protein E1 * / Forkhead box protein E3 *ENSDARG0000006289211
foxd1 / forkhead box D1 / FOXD2* / Q61345* / O35392* / O60548* / Q16676* / forkhead box D2* / Forkhead box protein D2 * / Forkhead box protein D1 *ENSDARG0000002917911
foxg1b / forkhead box G1bENSDARG0000003270511
foxg1c / forkhead box G1cENSDARG0000006838011
zgc:162612 / FOXD1* / FOXD2* / O60548* / Q61345* / Q16676* / O35392* / forkhead box D1* / forkhead box D2* / Forkhead box protein D1 * / Forkhead box protein D2 *ENSDARG0000007969911
foxg1d / forkhead box G1dENSDARG0000007005311
foxh1 / forkhead box H1 / O75593* / O88621* / Forkhead box protein H1 *ENSDARG0000005563010
foxe1 / forkhead box E1 / FOXE3* / Q9QY14* / O00358* / Q13461* / Q8R2I0* / forkhead box E3* / Forkhead box protein E3 * / Forkhead box protein E1 *ENSDARG0000007926610
foxq2 / forkhead box Q2ENSDARG0000007139410


Protein motifs (from Interpro)
Interpro ID Name
 IPR001766  Fork head domain
 IPR011991  ArsR-like helix-turn-helix domain
 IPR030456  Fork head domain conserved site 2
 IPR032354  FOXP, coiled-coil domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IEA
 biological_processGO:0009653 anatomical structure morphogenesis IBA
 biological_processGO:0030154 cell differentiation IBA
 biological_processGO:0042129 regulation of T cell proliferation IMP
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding IBA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA


Pathways (from Reactome)
Pathway description
RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000056 pharynx pharynx inflammatory , abnormal
pharynx has extra parts of type T cell , abnormal
pharynx T cell increased amount , abnormal
Show

 ZFA:0000354 gill gill inflammatory , abnormal
gill has extra parts of type T cell , abnormal
Show

 ZFA:0000368 integument integument inflammatory , abnormal
integument has extra parts of type T cell , abnormal
integument T cell increased amount , abnormal
Show

 ZFA:0000554 olfactory epithelium olfactory epithelium inflammatory , abnormal
olfactory epithelium has extra parts of type T cell , abnormal
olfactory epithelium T cell increased amount , abnormal
Show

 ZFA:0000667 gill filament gill filament swollen , abnormal
gill filament T cell increased amount , abnormal
Show

 ZFA:0001094 whole organism whole organism increased amount , abnormal
whole organism viability , abnormal
whole organism decreased length , abnormal
whole organism decreased weight , abnormal
Show

 ZFA:0001338 intestine intestine swollen , abnormal
intestine has extra parts of type T cell , abnormal
intestine T cell increased amount , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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