ENSDARG00000057624


Danio rerio

Features
Gene ID: ENSDARG00000057624
  
Biological name :cops5
  
Synonyms : COP9 signalosome subunit 5 / cops5 / Q6PC30
  
Possible biological names infered from orthology : COP9 signalosome complex subunit 5 / O35864 / Q92905
  
Species: Danio rerio
  
Chr. number: 24
Strand: 1
Band:
Gene start: 23716918
Gene end: 23725371
  
Corresponding Affymetrix probe sets: Dr.7424.1.A1_at (Zebrafish Array)   Dr.7424.2.S1_at (Zebrafish Array)   Dr.7424.3.A1_at (Zebrafish Array)   NM_200725_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000074782
NCBI entrez gene - 393698     See in Manteia.
RefSeq - NM_200725
RefSeq Peptide - NP_957019
swissprot - Q6PC30
ZFIN ID - ZDB-GENE-040426-1686
Ensembl - ENSDARG00000057624
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 COPS5ENSGALG00000030843Gallus gallus
 COPS5ENSG00000121022Homo sapiens
 Cops5ENSMUSG00000025917Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000555  JAB1/MPN/MOV34 metalloenzyme domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0043066 negative regulation of apoptotic process ISS
 biological_processGO:0051091 positive regulation of DNA-binding transcription factor activity ISS
 cellular_componentGO:0005634 nucleus ISS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol ISS
 cellular_componentGO:0008021 synaptic vesicle IEA
 cellular_componentGO:0008180 COP9 signalosome IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 cellular_componentGO:0045202 synapse IEA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IEA
 molecular_functionGO:0004222 metalloendopeptidase activity IEA
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008237 metallopeptidase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
DNA Damage Recognition in GG-NER
Formation of TC-NER Pre-Incision Complex
Cargo recognition for clathrin-mediated endocytosis
Neddylation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000038030 rbx1 / ring-box 1, E3 ubiquitin protein ligase / P62878* / P62877* / ring-box 1* / E3 ubiquitin-protein ligase RBX1 E3 ubiquitin-protein ligase RBX1, N-terminally processed*  / reaction
 ENSDARG00000007989 nedd8 / neural precursor cell expressed, developmentally down-regulated 8 / P29595* / Q15843*  / reaction
 ENSDARG00000060510 cul4b / cullin 4B / A2A432* / Q13620*  / reaction
 ENSDARG00000096578 cul4a / cullin 4A / Q13619* / Q3TCH7*  / reaction
 ENSDARG00000031203 commd1 / copper metabolism (Murr1) domain containing 1 / Q8K4M5* / Q8N668* / Gm28048* / COMM domain-containing protein 1 * / copper metabolism domain containing 1*  / reaction






 

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