Manteia

ENSDARG00000059812

Danio rerio

Features

Gene ID:	ENSDARG00000059812

Biological name :	sin3ab

Synonyms :	sin3ab / SIN3 transcription regulator family member Ab

Possible biological names infered from orthology :	Mus musculus transcriptional regulator, SIN3A (yeast) (Sin3a), transcript variant 4, mRNA. / Q60520 / Q96ST3 / SIN3A / SIN3 transcription regulator family member A

Species:	Danio rerio

Chr. number:	7
Strand:	-1
Band:
Gene start:	48345747
Gene end:	48396195

Corresponding Affymetrix probe sets:	Dr.4317.1.A1_at (Zebrafish Array)

Cross references:	Ensembl peptide - ENSDARP00000077990 Ensembl peptide - ENSDARP00000149185 Ensembl peptide - ENSDARP00000143146 NCBI entrez gene - 323346 See in Manteia. RefSeq - XM_002662877 RefSeq - XM_009303423 swissprot - E7F0R9 swissprot - A0A1L1QZM2 ZFIN ID - ZDB-GENE-030131-2066 Ensembl - ENSDARG00000059812

See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed

Ortholog prediction (from Ensembl)

Paralog prediction (from Ensembl)

Paralog name	ID	Similarity(%)
sin3aa / SIN3 transcription regulator family member Aa / SIN3A* / Q96ST3* / Q60520* / SIN3 transcription regulator family member A* / Mus musculus transcriptional regulator, SIN3A (yeast) (...	ENSDARG00000079716	77
sin3b / SIN3 transcription regulator family member B / O75182* / Q62141* / transcriptional regulator, SIN3B (yeast)*	ENSDARG00000062472	49

Protein motifs (from Interpro)

Interpro ID	Name
IPR003822	Paired amphipathic helix
IPR013194	Histone deacetylase interacting domain
IPR031693	Sin3, C-terminal

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
biological_process	GO:0000122	negative regulation of transcription by RNA polymerase II	IBA
biological_process	GO:0006355	regulation of transcription, DNA-templated	IEA
biological_process	GO:0016575	histone deacetylation	IBA
biological_process	GO:1903507	negative regulation of nucleic acid-templated transcription	IEA
cellular_component	GO:0005634	nucleus	IEA
cellular_component	GO:0016580	Sin3 complex	IBA
molecular_function	GO:0003714	transcription corepressor activity	IEA
molecular_function	GO:0004407	histone deacetylase activity	IBA

Pathways (from Reactome)

Pathway description

SUMOylation of transcription cofactors

Phenotype (from MGI, Zfin or HPO)

Phenotype

Definition

Genetic BG

No match

Interacting proteins (from Reactome)

Interactor ID	Name	Interaction type
ENSDARG00000007438	ube2ib / Q9W6H5 / ubiquitin-conjugating enzyme E2Ib / UBE2I* / P63279* / ubiquitin conjugating enzyme E2 I*	/ reaction
ENSDARG00000044267	sumo1 / Q7SZR5 / small ubiquitin-like modifier 1 / P63166* / P63165* / Small ubiquitin-related modifier 1 *	/ reaction / complex
ENSDARG00000105359	Q4QRF4 / FP325123.1 / Histone H3.2	/ complex
ENSDARG00000069706	prmt6 / protein arginine methyltransferase 6 / Q96LA8*	/ complex / reaction
ENSDARG00000015427	hdac1 / histone deacetylase 1 / O09106* / Q13547* / Gm10093*	/ complex / reaction
ENSDARG00000068436	Q6PI20 / h3f3b.1 / H3 histone, family 3B.1 / H3F3B* / H3F3C* / P84243* / Q6NXT2* / H3 histone family member 3C* / H3 histone family member 3B*	/ complex
ENSDARG00000105345	zgc:173552	/ complex
ENSDARG00000052649	Q9DDJ0 / ube2ia / ubiquitin-conjugating enzyme E2Ia / UBE2I* / P63280* / P63279* / ubiquitin conjugating enzyme E2 I*	/ reaction
ENSDARG00000087646	runx1 / runt-related transcription factor 1 / Q01196*	/ complex / reaction

1 s.

External programs and data are copyrighted by and are the property of their respective authors. The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation
		© Olivier Tassy / Olivier Pourquie 2007-2024 contact: otassy@igbmc.fr