ENSDARG00000060410


Danio rerio

Features
Gene ID: ENSDARG00000060410
  
Biological name :thbs2a
  
Synonyms : thbs2a / thrombospondin 2a
  
Possible biological names infered from orthology : P35442 / Q03350 / THBS2 / thrombospondin 2
  
Species: Danio rerio
  
Chr. number: 13
Strand: 1
Band:
Gene start: 35635672
Gene end: 35677353
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000148257
Ensembl peptide - ENSDARP00000079472
Ensembl peptide - ENSDARP00000124920
NCBI entrez gene - 100535241     See in Manteia.
swissprot - F1RAW4
swissprot - F8W5Z7
ZFIN ID - ZDB-GENE-020708-2
Ensembl - ENSDARG00000060410
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 THBS2ENSGALG00000011200Gallus gallus
 THBS2ENSG00000186340Homo sapiens
 Thbs2ENSMUSG00000023885Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
thbs2b / thrombospondin 2b / THBS2* / Q03350* / P35442* / thrombospondin 2*ENSDARG0000007381078
thbs1b / thrombospondin 1b / THBS1* / P07996* / thrombospondin 1*ENSDARG0000001078562
thbs4a / thrombospondin 4a / THBS4* / P35443* / thrombospondin 4*ENSDARG0000010277733
thbs3a / thrombospondin 3a / THBS3* / Q05895* / P49746* / thrombospondin 3*ENSDARG0000007764133
thbs4b / thrombospondin 4b / THBS4* / Q9Z1T2* / P35443* / thrombospondin 4*ENSDARG0000002007233
Q1L8P7 / thbs3b / thrombospondin 3b / THBS3* / Q05895* / P49746* / thrombospondin 3*ENSDARG0000001206032
COMP / si:ch211-43f4.1 / P49747* / Q9R0G6* / cartilage oligomeric matrix protein*ENSDARG0000009843130


Protein motifs (from Interpro)
Interpro ID Name
 IPR000742  EGF-like domain
 IPR000884  Thrombospondin type-1 (TSP1) repeat
 IPR001007  VWFC domain
 IPR001791  Laminin G domain
 IPR001881  EGF-like calcium-binding domain
 IPR003367  Thrombospondin, type 3-like repeat
 IPR008859  Thrombospondin, C-terminal
 IPR013032  EGF-like, conserved site
 IPR013320  Concanavalin A-like lectin/glucanase domain superfamily
 IPR015455  Thrombospondin-2
 IPR017897  Thrombospondin, type 3 repeat
 IPR024731  EGF domain
 IPR028974  TSP type-3 repeat


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007155 cell adhesion IEA
 biological_processGO:0016525 negative regulation of angiogenesis IEA
 biological_processGO:0030198 extracellular matrix organization IEA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0031012 extracellular matrix IEA
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0008201 heparin binding IEA


Pathways (from Reactome)
Pathway description
Signaling by PDGF
O-glycosylation of TSR domain-containing proteins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000038139 pdgfbb / platelet-derived growth factor beta polypeptide b / PDGFB* / P01127* / platelet derived growth factor subunit B* / platelet derived growth factor, B polypeptide*  / reaction / complex
 ENSDARG00000110069 pdgfaa / platelet-derived growth factor alpha polypeptide a / PDGFA* / P04085* / platelet derived growth factor subunit A*  / complex / reaction
 ENSDARG00000086778 pdgfba / platelet-derived growth factor beta polypeptide a / PDGFB* / P01127* / platelet derived growth factor subunit B* / platelet derived growth factor, B polypeptide*  / reaction / complex






 

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