ENSGALG00000011200


Gallus gallus

Features
Gene ID: ENSGALG00000011200
  
Biological name :THBS2
  
Synonyms : THBS2 / thrombospondin-2 precursor
  
Possible biological names infered from orthology : P35442 / Q03350 / thrombospondin 2
  
Species: Gallus gallus
  
Chr. number: 3
Strand: 1
Band:
Gene start: 41483185
Gene end: 41514674
  
Corresponding Affymetrix probe sets: Gga.797.1.S1_at (Chicken Array)   GgaAffx.21822.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000018239
NCBI entrez gene - 414837     See in Manteia.
RefSeq - NM_001001755
RefSeq - XM_015284051
RefSeq - XM_015284053
RefSeq Peptide - NP_001001755
swissprot - E1C3P2
Ensembl - ENSGALG00000011200
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 thbs2aENSDARG00000060410Danio rerio
 thbs2bENSDARG00000073810Danio rerio
 THBS2ENSG00000186340Homo sapiens
 Thbs2ENSMUSG00000023885Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
THBS1 / thrombospondin-1 precursor / P07996* / thrombospondin 1*ENSGALG0000000962661
THBS4 / Gallus gallus thrombospondin 4 (THBS4), mRNA. / P35443* / Q9Z1T2* / thrombospondin 4*ENSGALG0000001480433
COMP / cartilage oligomeric matrix protein / P49747* / Q9R0G6*ENSGALG0000000328330


Protein motifs (from Interpro)
Interpro ID Name
 IPR000742  EGF-like domain
 IPR000884  Thrombospondin type-1 (TSP1) repeat
 IPR001007  VWFC domain
 IPR001791  Laminin G domain
 IPR001881  EGF-like calcium-binding domain
 IPR003367  Thrombospondin, type 3-like repeat
 IPR008859  Thrombospondin, C-terminal
 IPR013032  EGF-like, conserved site
 IPR013320  Concanavalin A-like lectin/glucanase domain superfamily
 IPR015455  Thrombospondin-2
 IPR017897  Thrombospondin, type 3 repeat
 IPR024731  EGF domain
 IPR028974  TSP type-3 repeat


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007155 cell adhesion IEA
 biological_processGO:0016525 negative regulation of angiogenesis IEA
 biological_processGO:0030198 extracellular matrix organization IEA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005604 basement membrane IEA
 cellular_componentGO:0005615 extracellular space IEA
 cellular_componentGO:0031012 extracellular matrix IEA
 cellular_componentGO:0031091 platelet alpha granule IEA
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0008201 heparin binding IEA


Pathways (from Reactome)
Pathway description
Signaling by PDGF
O-glycosylation of TSR domain-containing proteins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000012178 PDGFB / platelet derived growth factor subunit B / P01127* / platelet derived growth factor, B polypeptide*  / complex / reaction
 ENSGALG00000003642 PDGFA / platelet derived growth factor subunit A / P04085*  / complex / reaction






 

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