ENSGALG00000014804


Gallus gallus

Features
Gene ID: ENSGALG00000014804
  
Biological name :THBS4
  
Synonyms : Gallus gallus thrombospondin 4 (THBS4), mRNA. / THBS4
  
Possible biological names infered from orthology : P35443 / Q9Z1T2 / thrombospondin 4
  
Species: Gallus gallus
  
Chr. number: Z
Strand: -1
Band:
Gene start: 22015578
Gene end: 22053824
  
Corresponding Affymetrix probe sets: Gga.1980.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000023854
NCBI entrez gene - 396306     See in Manteia.
RefSeq - NM_001321549
RefSeq - XM_004937318
RefSeq - XM_424763
RefSeq Peptide - NP_001308478
swissprot - F1NBP0
Ensembl - ENSGALG00000014804
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 thbs4aENSDARG00000102777Danio rerio
 thbs4bENSDARG00000020072Danio rerio
 THBS4ENSG00000113296Homo sapiens
 Thbs4ENSMUSG00000021702Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
COMP / cartilage oligomeric matrix protein / P49747* / Q9R0G6*ENSGALG0000000328357
THBS2 / thrombospondin-2 precursor / P35442* / Q03350* / thrombospondin 2*ENSGALG0000001120042
THBS1 / thrombospondin-1 precursor / P07996* / thrombospondin 1*ENSGALG0000000962641


Protein motifs (from Interpro)
Interpro ID Name
 IPR000742  EGF-like domain
 IPR001791  Laminin G domain
 IPR001881  EGF-like calcium-binding domain
 IPR003367  Thrombospondin, type 3-like repeat
 IPR008859  Thrombospondin, C-terminal
 IPR013032  EGF-like, conserved site
 IPR013320  Concanavalin A-like lectin/glucanase domain superfamily
 IPR017897  Thrombospondin, type 3 repeat
 IPR018097  EGF-like calcium-binding, conserved site
 IPR024665  Thrombospondin/cartilage oligomeric matrix protein, coiled-coil domain
 IPR028974  TSP type-3 repeat


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001938 positive regulation of endothelial cell proliferation IEA
 biological_processGO:0007155 cell adhesion IEA
 biological_processGO:0016525 negative regulation of angiogenesis IEA
 biological_processGO:0030198 extracellular matrix organization IEA
 biological_processGO:0034103 regulation of tissue remodeling IEA
 biological_processGO:0034976 response to endoplasmic reticulum stress IEA
 biological_processGO:0048266 behavioral response to pain IEA
 biological_processGO:0050731 positive regulation of peptidyl-tyrosine phosphorylation IEA
 biological_processGO:0051451 myoblast migration IEA
 biological_processGO:0071603 endothelial cell-cell adhesion IEA
 biological_processGO:0090023 positive regulation of neutrophil chemotaxis IEA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005604 basement membrane IEA
 cellular_componentGO:0005615 extracellular space IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0016529 sarcoplasmic reticulum IEA
 cellular_componentGO:0031012 extracellular matrix IEA
 molecular_functionGO:0005178 integrin binding IEA
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0008201 heparin binding IEA


Pathways (from Reactome)
Pathway description
Signaling by PDGF


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000003642 PDGFA / platelet derived growth factor subunit A / P04085*  / complex / reaction
 ENSGALG00000012178 PDGFB / platelet derived growth factor subunit B / P01127* / platelet derived growth factor, B polypeptide*  / complex / reaction






 

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