ENSGALG00000003283


Gallus gallus

Features
Gene ID: ENSGALG00000003283
  
Biological name :COMP
  
Synonyms : cartilage oligomeric matrix protein / COMP
  
Possible biological names infered from orthology : P49747 / Q9R0G6
  
Species: Gallus gallus
  
Chr. number: 28
Strand: 1
Band:
Gene start: 3800421
Gene end: 3815388
  
Corresponding Affymetrix probe sets: Gga.11142.1.S1_at (Chicken Array)   Gga.11142.2.S1_s_at (Chicken Array)   Gga.3931.1.S1_at (Chicken Array)   GgaAffx.25795.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000005183
NCBI entrez gene - 420120     See in Manteia.
RefSeq - XM_015300132
RefSeq - XM_418238
RefSeq - XM_015300133
RefSeq - XM_015300134
swissprot - E1C8N1
Ensembl - ENSGALG00000003283
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 COMPENSDARG00000098431Danio rerio
 COMPENSG00000105664Homo sapiens
 CompENSMUSG00000031849Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
THBS4 / Gallus gallus thrombospondin 4 (THBS4), mRNA. / P35443* / Q9Z1T2* / thrombospondin 4*ENSGALG0000001480471
THBS2 / thrombospondin-2 precursor / P35442* / Q03350* / thrombospondin 2*ENSGALG0000001120048
THBS1 / thrombospondin-1 precursor / P07996* / thrombospondin 1*ENSGALG0000000962648


Protein motifs (from Interpro)
Interpro ID Name
 IPR000742  EGF-like domain
 IPR001881  EGF-like calcium-binding domain
 IPR003367  Thrombospondin, type 3-like repeat
 IPR008859  Thrombospondin, C-terminal
 IPR013032  EGF-like, conserved site
 IPR013320  Concanavalin A-like lectin/glucanase domain superfamily
 IPR017897  Thrombospondin, type 3 repeat
 IPR018097  EGF-like calcium-binding, conserved site
 IPR024665  Thrombospondin/cartilage oligomeric matrix protein, coiled-coil domain
 IPR028974  TSP type-3 repeat


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0003417 growth plate cartilage development IEA
 biological_processGO:0007155 cell adhesion IEA
 biological_processGO:0030198 extracellular matrix organization IEA
 biological_processGO:0043066 negative regulation of apoptotic process IEA
 biological_processGO:0060173 limb development IEA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space IEA
 cellular_componentGO:0031012 extracellular matrix IEA
 molecular_functionGO:0002020 protease binding IEA
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0005518 collagen binding IEA
 molecular_functionGO:0008201 heparin binding IEA
 molecular_functionGO:0043395 heparan sulfate proteoglycan binding IEA


Pathways (from Reactome)
Pathway description
Integrin cell surface interactions
ECM proteoglycans


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000000379 ITGB3 / P05106* / O54890* / AC068234.1* / Integrin beta-3 * / integrin subunit beta 3*  / reaction / complex
 ENSGALG00000003283 COMP / cartilage oligomeric matrix protein / P49747* / Q9R0G6*  / complex
 ENSGALG00000007145 ITGB1 / integrin subunit beta 1 / P05556* / P09055* / Integrin beta-1 *  / reaction / complex
 ENSGALG00000016478 MATN3 / O42401 / Matrilin-3 / O15232* / O35701*  / complex / reaction
 ENSGALG00000043185 MATN1 / matrilin 1, cartilage matrix protein / P21941* / P51942* / Cartilage matrix protein *  / reaction / complex






 

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