ENSDARG00000062139


Danio rerio

Features
Gene ID: ENSDARG00000062139
  
Biological name :eif2ak3
  
Synonyms : eif2ak3 / eukaryotic translation initiation factor 2-alpha kinase 3
  
Possible biological names infered from orthology : Q9NZJ5
  
Species: Danio rerio
  
Chr. number: 13
Strand: 1
Band:
Gene start: 13945218
Gene end: 14004546
  
Corresponding Affymetrix probe sets: Dr.15219.1.S1_at (Zebrafish Array)   Dr.15219.1.S1_a_at (Zebrafish Array)   Dr.15219.2.S1_a_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000083934
Ensembl peptide - ENSDARP00000120826
NCBI entrez gene - 559564     See in Manteia.
swissprot - B8JI14
swissprot - F1Q9L5
ZFIN ID - ZDB-GENE-050414-2
Ensembl - ENSDARG00000062139
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 EIF2AK3ENSGALG00000015958Gallus gallus
 Q9NZJ5ENSG00000172071Homo sapiens
 Eif2ak3ENSMUSG00000031668Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
eif2ak2 / eukaryotic translation initiation factor 2-alpha kinase 2 / P19525*ENSDARG0000006872915
pkz / protein kinase containing Z-DNA binding domains / P19525* / EIF2AK2* / eukaryotic translation initiation factor 2 alpha kinase 2*ENSDARG0000005239613
eif2ak1 / eukaryotic translation initiation factor 2-alpha kinase 1 / Q9BQI3* / Q9Z2R9*ENSDARG0000009318213


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR011047  Quinoprotein alcohol dehydrogenase-like superfamily
 IPR017441  Protein kinase, ATP binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001666 response to hypoxia IDA
 biological_processGO:0006468 protein phosphorylation IEA
 cellular_componentGO:0005575 cellular_component ND
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0005524 ATP binding IEA


Pathways (from Reactome)
Pathway description
PERK regulates gene expression


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000062139 eif2ak3 / eukaryotic translation initiation factor 2-alpha kinase 3 / Q9NZJ5*  / complex / reaction
 ENSDARG00000052178 eif2s1b / eukaryotic translation initiation factor 2, subunit 1 alpha b / Q6ZWX6* / P05198* / EIF2S1* / Eukaryotic translation initiation factor 2 subunit 1 * / eukaryotic translation initi...  / reaction
 ENSDARG00000005827 eif2s1a / eukaryotic translation initiation factor 2, subunit 1 alpha a / Q6ZWX6* / P05198* / EIF2S1* / Eukaryotic translation initiation factor 2 subunit 1 * / eukaryotic translation initi...  / reaction






 

1 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr