ENSDARG00000069968


Danio rerio

Features
Gene ID: ENSDARG00000069968
  
Biological name :pcsk7
  
Synonyms : pcsk7 / proprotein convertase subtilisin/kexin type 7
  
Possible biological names infered from orthology : Q16549 / Q61139
  
Species: Danio rerio
  
Chr. number: 15
Strand: 1
Band:
Gene start: 518092
Gene end: 542133
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000128034
NCBI entrez gene - 100009656     See in Manteia.
RefSeq - NM_001320428
RefSeq Peptide - NP_001307357
swissprot - F1R440
ZFIN ID - ZDB-GENE-030131-7293
Ensembl - ENSDARG00000069968
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PCSK7ENSGALG00000029220Gallus gallus
 PCSK7ENSG00000160613Homo sapiens
 Pcsk7ENSMUSG00000035382Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
pcsk5a / proprotein convertase subtilisin/kexin type 5a / PCSK5* / Q92824* / Q04592* / proprotein convertase subtilisin/kexin type 5*ENSDARG0000006753736
furina / furin (paired basic amino acid cleaving enzyme) a / FURIN* / P09958* / furin, paired basic amino acid cleaving enzyme*ENSDARG0000006290935
furinb / furin (paired basic amino acid cleaving enzyme) b / FURIN* / P23188* / P09958* / furin, paired basic amino acid cleaving enzyme*ENSDARG0000007097134
pcsk1 / proprotein convertase subtilisin/kexin type 1 / P29120* / P63239* / Neuroendocrine convertase 1 *ENSDARG0000000260033
pcsk2 / proprotein convertase subtilisin/kexin type 2 / P16519*ENSDARG0000001945130
pcsk5b / proprotein convertase subtilisin/kexin type 5b / PCSK5* / Q92824* / proprotein convertase subtilisin/kexin type 5*ENSDARG0000006051828
pcsk6 / proprotein convertase subtilisin/kexin type 6 / P29122*ENSDARG0000010457413


Protein motifs (from Interpro)
Interpro ID Name
 IPR000209  Peptidase S8/S53 domain
 IPR002884  P domain
 IPR008979  Galactose-binding-like domain superfamily
 IPR015500  Peptidase S8, subtilisin-related
 IPR022398  Peptidase S8, subtilisin, His-active site
 IPR023827  Peptidase S8, subtilisin, Asp-active site
 IPR023828  Peptidase S8, subtilisin, Ser-active site
 IPR032815  Peptidase S8, pro-domain
 IPR034182  Kexin/furin catalytic domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001654 eye development IMP
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0007420 brain development IMP
 biological_processGO:0043009 chordate embryonic development IMP
 biological_processGO:0048840 otolith development IMP
 molecular_functionGO:0004252 serine-type endopeptidase activity IEA
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008236 serine-type peptidase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000008 brain brain morphology , abnormal
brain immature , abnormal
Show

 ZFA:0000107 eye eye morphology , abnormal
Show

 ZFA:0001094 whole organism whole organism dead , abnormal
Show

 ZFA:0001617 otolith otolith decreased amount , abnormal
otolith increased amount , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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