ENSDARG00000019451


Danio rerio

Features
Gene ID: ENSDARG00000019451
  
Biological name :pcsk2
  
Synonyms : pcsk2 / proprotein convertase subtilisin/kexin type 2
  
Possible biological names infered from orthology : P16519 / P21661
  
Species: Danio rerio
  
Chr. number: 13
Strand: 1
Band:
Gene start: 912123
Gene end: 977652
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000131068
NCBI entrez gene - 100004460     See in Manteia.
RefSeq - NM_001142266
RefSeq Peptide - NP_001135738
swissprot - A0A0R4IAA7
swissprot - B6VCA2
ZFIN ID - ZDB-GENE-090608-1
Ensembl - ENSDARG00000019451
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PCSK2ENSGALG00000008734Gallus gallus
 PCSK2ENSG00000125851Homo sapiens
 Pcsk2ENSMUSG00000027419Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
furinb / furin (paired basic amino acid cleaving enzyme) b / FURIN* / P23188* / P09958* / furin, paired basic amino acid cleaving enzyme*ENSDARG0000007097142
pcsk1 / proprotein convertase subtilisin/kexin type 1 / P29120* / P63239* / Neuroendocrine convertase 1 *ENSDARG0000000260042
furina / furin (paired basic amino acid cleaving enzyme) a / FURIN* / P09958* / furin, paired basic amino acid cleaving enzyme*ENSDARG0000006290942
pcsk5a / proprotein convertase subtilisin/kexin type 5a / PCSK5* / Q92824* / Q04592* / proprotein convertase subtilisin/kexin type 5*ENSDARG0000006753739
pcsk7 / proprotein convertase subtilisin/kexin type 7 / Q16549*ENSDARG0000006996833
pcsk5b / proprotein convertase subtilisin/kexin type 5b / PCSK5* / Q92824* / proprotein convertase subtilisin/kexin type 5*ENSDARG0000006051831
pcsk6 / proprotein convertase subtilisin/kexin type 6 / P29122*ENSDARG0000010457413


Protein motifs (from Interpro)
Interpro ID Name
 IPR000209  Peptidase S8/S53 domain
 IPR002884  P domain
 IPR008979  Galactose-binding-like domain superfamily
 IPR015500  Peptidase S8, subtilisin-related
 IPR032815  Peptidase S8, pro-domain
 IPR034182  Kexin/furin catalytic domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 molecular_functionGO:0004252 serine-type endopeptidase activity IEA
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008236 serine-type peptidase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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