ENSDARG00000060518


Danio rerio

Features
Gene ID: ENSDARG00000060518
  
Biological name :pcsk5b
  
Synonyms : pcsk5b / proprotein convertase subtilisin/kexin type 5b
  
Possible biological names infered from orthology : PCSK5 / proprotein convertase subtilisin/kexin type 5 / Q04592 / Q92824
  
Species: Danio rerio
  
Chr. number: 8
Strand: -1
Band:
Gene start: 38649989
Gene end: 38810233
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000079739
swissprot - F1R027
ZFIN ID - ZDB-GENE-070822-7
Ensembl - ENSDARG00000060518
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000033256Gallus gallus
 ENSGALG00000015164Gallus gallus
 PCSK5ENSG00000099139Homo sapiens
 Pcsk5ENSMUSG00000024713Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
pcsk5a / proprotein convertase subtilisin/kexin type 5a / PCSK5* / Q92824* / Q04592* / proprotein convertase subtilisin/kexin type 5*ENSDARG0000006753765
furinb / furin (paired basic amino acid cleaving enzyme) b / FURIN* / P23188* / P09958* / furin, paired basic amino acid cleaving enzyme*ENSDARG0000007097138
furina / furin (paired basic amino acid cleaving enzyme) a / FURIN* / P09958* / furin, paired basic amino acid cleaving enzyme*ENSDARG0000006290937
pcsk6 / proprotein convertase subtilisin/kexin type 6 / P29122*ENSDARG0000010457435
pcsk1 / proprotein convertase subtilisin/kexin type 1 / P29120* / P63239* / Neuroendocrine convertase 1 *ENSDARG0000000260031
pcsk2 / proprotein convertase subtilisin/kexin type 2 / P16519*ENSDARG0000001945129
pcsk7 / proprotein convertase subtilisin/kexin type 7 / Q16549*ENSDARG0000006996828


Protein motifs (from Interpro)
Interpro ID Name
 IPR000209  Peptidase S8/S53 domain
 IPR000742  EGF-like domain
 IPR002884  P domain
 IPR006212  Furin-like repeat
 IPR008979  Galactose-binding-like domain superfamily
 IPR009030  Growth factor receptor cysteine-rich domain superfamily
 IPR010909  PLAC
 IPR022398  Peptidase S8, subtilisin, His-active site
 IPR023828  Peptidase S8, subtilisin, Ser-active site
 IPR032778  Growth factor receptor domain 4
 IPR034182  Kexin/furin catalytic domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 molecular_functionGO:0004252 serine-type endopeptidase activity IEA
 molecular_functionGO:0008233 peptidase activity IEA


Pathways (from Reactome)
Pathway description
NGF processing


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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