ENSGALG00000033256


Gallus gallus

Features
Gene ID: ENSGALG00000033256
  
Biological name :
  
Synonyms :
  
Possible biological names infered from orthology : PCSK5 / proprotein convertase subtilisin/kexin type 5 / Q04592 / Q92824
  
Species: Gallus gallus
  
Chr. number: Z
Strand: 1
Band:
Gene start: 37062725
Gene end: 37257739
  
Corresponding Affymetrix probe sets: Gga.12660.2.S1_a_at (Chicken Array)   Gga.14835.1.S1_at (Chicken Array)   Gga.247.1.S1_at (Chicken Array)   GgaAffx.9641.1.S1_at (Chicken Array)   GgaAffx.9643.1.S1_at (Chicken Array)   GgaAffx.9643.2.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000045160
Ensembl peptide - ENSGALP00000050829
NCBI entrez gene - 395456     See in Manteia.
RefSeq - XM_424841
swissprot - A0A1D5NXR1
swissprot - A0A1D5PDI4
Ensembl - ENSGALG00000033256
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 pcsk5aENSDARG00000067537Danio rerio
 pcsk5bENSDARG00000060518Danio rerio
 PCSK5ENSG00000099139Homo sapiens
 Pcsk5ENSMUSG00000024713Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PCSK6 / proprotein convertase subtilisin/kexin type 6 / P29122*ENSGALG0000003007656
FURIN / furin, paired basic amino acid cleaving enzyme / P09958* / P23188*ENSGALG0000000834140
PCSK4 / proprotein convertase subtilisin/kexin type 4 / P29121* / Q6UW60*ENSGALG0000002638432
PCSK1 / proprotein convertase subtilisin/kexin type 1 / P29120* / P63239* / Neuroendocrine convertase 1 *ENSGALG0000001468132
PCSK2 / proprotein convertase subtilisin/kexin type 2 / P16519* / P21661*ENSGALG0000000873429
PCSK7 / proprotein convertase subtilisin/kexin type 7 / Q16549* / Q61139*ENSGALG0000002922028
PCSK5* / Q04592* / Q92824* / proprotein convertase subtilisin/kexin type 5*ENSGALG000000151641


Protein motifs (from Interpro)
Interpro ID Name
 IPR000209  Peptidase S8/S53 domain
 IPR002884  P domain
 IPR006212  Furin-like repeat
 IPR008979  Galactose-binding-like domain superfamily
 IPR009030  Growth factor receptor cysteine-rich domain superfamily
 IPR010909  PLAC
 IPR011641  Tyrosine-protein kinase ephrin type A/B receptor-like
 IPR015500  Peptidase S8, subtilisin-related
 IPR022398  Peptidase S8, subtilisin, His-active site
 IPR023827  Peptidase S8, subtilisin, Asp-active site
 IPR023828  Peptidase S8, subtilisin, Ser-active site
 IPR032778  Growth factor receptor domain 4
 IPR032815  Peptidase S8, pro-domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 molecular_functionGO:0004252 serine-type endopeptidase activity IEA
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008236 serine-type peptidase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA


Pathways (from Reactome)
Pathway description
NGF processing


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000002556 NGF / nerve growth factor / P01138* / P01139* / Beta-nerve growth factor *  / reaction






 

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