ENSGALG00000026384


Gallus gallus

Features
Gene ID: ENSGALG00000026384
  
Biological name :PCSK4
  
Synonyms : PCSK4 / proprotein convertase subtilisin/kexin type 4
  
Possible biological names infered from orthology : P29121 / Q6UW60
  
Species: Gallus gallus
  
Chr. number: 28
Strand: 1
Band:
Gene start: 3250482
Gene end: 3255046
  
Corresponding Affymetrix probe sets: GgaAffx.9672.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000040867
NCBI entrez gene - 100859150     See in Manteia.
RefSeq - XM_015299950
swissprot - R4GFR5
Ensembl - ENSGALG00000026384
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PCSK4ENSG00000115257Homo sapiens
 Pcsk4ENSMUSG00000020131Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
FURIN / furin, paired basic amino acid cleaving enzyme / P09958* / P23188*ENSGALG0000000834152
PCSK5* / Q04592* / Q92824* / proprotein convertase subtilisin/kexin type 5*ENSGALG0000003325645
PCSK6 / proprotein convertase subtilisin/kexin type 6 / P29122*ENSGALG0000003007644
PCSK1 / proprotein convertase subtilisin/kexin type 1 / P29120* / P63239* / Neuroendocrine convertase 1 *ENSGALG0000001468140
PCSK2 / proprotein convertase subtilisin/kexin type 2 / P16519* / P21661*ENSGALG0000000873437
PCSK7 / proprotein convertase subtilisin/kexin type 7 / Q16549* / Q61139*ENSGALG0000002922032
PCSK5* / Q04592* / Q92824* / proprotein convertase subtilisin/kexin type 5*ENSGALG000000151641


Protein motifs (from Interpro)
Interpro ID Name
 IPR000209  Peptidase S8/S53 domain
 IPR002884  P domain
 IPR006212  Furin-like repeat
 IPR008979  Galactose-binding-like domain superfamily
 IPR009030  Growth factor receptor cysteine-rich domain superfamily
 IPR015500  Peptidase S8, subtilisin-related
 IPR022398  Peptidase S8, subtilisin, His-active site
 IPR032815  Peptidase S8, pro-domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0007339 binding of sperm to zona pellucida IEA
 biological_processGO:0007340 acrosome reaction IEA
 biological_processGO:0009566 fertilization IEA
 biological_processGO:0016485 protein processing IEA
 biological_processGO:0022414 reproductive process IEA
 biological_processGO:0048240 sperm capacitation IEA
 cellular_componentGO:0001669 acrosomal vesicle IEA
 cellular_componentGO:0002080 acrosomal membrane IEA
 molecular_functionGO:0004252 serine-type endopeptidase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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