ENSDARG00000071652


Danio rerio

Features
Gene ID: ENSDARG00000071652
  
Biological name :rrp8
  
Synonyms : ribosomal RNA processing 8, methyltransferase, homolog (yeast) / rrp8
  
Possible biological names infered from orthology : O43159 / Q9DB85 / ribosomal RNA processing 8 / Ribosomal RNA-processing protein 8
  
Species: Danio rerio
  
Chr. number: 15
Strand: -1
Band:
Gene start: 15221123
Gene end: 15230264
  
Corresponding Affymetrix probe sets: Dr.8475.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000128801
Ensembl peptide - ENSDARP00000153593
NCBI entrez gene - 797198     See in Manteia.
RefSeq - XM_001334650
RefSeq - XM_017351146
RefSeq - XM_021472910
swissprot - F1R692
ZFIN ID - ZDB-GENE-030131-8898
Ensembl - ENSDARG00000071652
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 RRP8ENSG00000132275Homo sapiens
 Rrp8ENSMUSG00000030888Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR007823  Ribosomal RNA processing protein 8
 IPR029063  S-adenosyl-L-methionine-dependent methyltransferase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000183 chromatin silencing at rDNA IBA
 biological_processGO:0032259 methylation IEA
 biological_processGO:0042149 cellular response to glucose starvation IBA
 biological_processGO:0046015 regulation of transcription by glucose IBA
 cellular_componentGO:0005677 chromatin silencing complex IBA
 cellular_componentGO:0005730 nucleolus IEA
 cellular_componentGO:0033553 rDNA heterochromatin IBA
 molecular_functionGO:0008168 methyltransferase activity IEA
 molecular_functionGO:0008757 S-adenosylmethionine-dependent methyltransferase activity IBA
 molecular_functionGO:0035064 methylated histone binding IBA


Pathways (from Reactome)
Pathway description
SIRT1 negatively regulates rRNA expression


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000026799 Q6DGD3 / suv39h1a / suppressor of variegation 3-9 homolog 1a / O54864* / O43463* / SUV39H1* / suppressor of variegation 3-9 1* / suppressor of variegation 3-9 homolog 1*  / reaction / complex
 ENSDARG00000055753 suv39h1b / suppressor of variegation 3-9 homolog 1b / O54864* / O43463* / SUV39H1* / suppressor of variegation 3-9 1* / suppressor of variegation 3-9 homolog 1*  / reaction / complex
 ENSDARG00000068436 Q6PI20 / h3f3b.1 / H3 histone, family 3B.1 / H3F3B* / H3F3C* / P84243* / Q6NXT2* / H3 histone family member 3C* / H3 histone family member 3B*  / complex / reaction
 ENSDARG00000068064 sirt1 / sirtuin 1 / Q96EB6*  / reaction / complex
 ENSDARG00000105345 zgc:173552  / reaction / complex
 ENSDARG00000105359 Q4QRF4 / FP325123.1 / Histone H3.2   / reaction / complex






 

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