ENSDARG00000026799


Danio rerio

Features
Gene ID: ENSDARG00000026799
  
Biological name :suv39h1a
  
Synonyms : Q6DGD3 / suppressor of variegation 3-9 homolog 1a / suv39h1a
  
Possible biological names infered from orthology : O43463 / O54864 / suppressor of variegation 3-9 1 / suppressor of variegation 3-9 homolog 1 / SUV39H1
  
Species: Danio rerio
  
Chr. number: 8
Strand: 1
Band:
Gene start: 23395469
Gene end: 23405105
  
Corresponding Affymetrix probe sets: Dr.6386.1.A1_at (Zebrafish Array)   Dr.6386.2.S1_at (Zebrafish Array)   NM_001003592_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000034818
NCBI entrez gene - 445198     See in Manteia.
RefSeq - NM_001003592
RefSeq Peptide - NP_001003592
swissprot - Q6DGD3
ZFIN ID - ZDB-GENE-040801-111
Ensembl - ENSDARG00000026799
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 O43463ENSG00000101945Homo sapiens
 O54864ENSMUSG00000039231Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
suv39h1b / suppressor of variegation 3-9 homolog 1b / O54864* / O43463* / SUV39H1* / suppressor of variegation 3-9 1* / suppressor of variegation 3-9 homolog 1*ENSDARG0000005575364
ehmt1b / euchromatic histone-lysine N-methyltransferase 1b / EHMT1* / Q5DW34* / Q9H9B1* / Histone-lysine N-methyltransferase EHMT1 * / euchromatic histone lysine methyltransferase 1*ENSDARG0000002663426
setdb1b / SET domain, bifurcated 1b / Q15047* / SETDB1* / SET domain bifurcated 1*ENSDARG0000009902126
Q1L8U8 / setdb1a / SET domain, bifurcated 1aENSDARG0000004124325
ehmt2 / euchromatic histone-lysine N-methyltransferase 2 / Q96KQ7* / euchromatic histone lysine methyltransferase 2*ENSDARG0000010232524
ehmt1a / euchromatic histone-lysine N-methyltransferase 1a / EHMT1* / Q5DW34* / Q9H9B1* / Histone-lysine N-methyltransferase EHMT1 * / euchromatic histone lysine methyltransferase 1*ENSDARG0000006815724
ash1l / ash1 (absent, small, or homeotic)-like (Drosophila) / Q99MY8* / Q9NR48* / Histone-lysine N-methyltransferase ASH1L * / ASH1 like histone lysine methyltransferase*ENSDARG0000007098121
setmar / SET domain and mariner transposase fusion gene / Q53H47* / Q80UJ9* / Histone-lysine N-methyltransferase SETMAR *ENSDARG0000007483621
ezh2 / enhancer of zeste 2 polycomb repressive complex 2 subunit / Q15910* / Q61188* / Histone-lysine N-methyltransferase EZH2 *ENSDARG0000001057120
setd2 / SET domain containing 2 / E9Q5F9* / Q9BYW2* / Histone-lysine N-methyltransferase SETD2 *ENSDARG0000006224420
nsd1a / nuclear receptor binding SET domain protein 1a / NSD1* / Q96L73* / nuclear receptor binding SET domain protein 1*ENSDARG0000006001619
nsd3 / nuclear receptor binding SET domain protein 3 / Q6P2L6* / Q9BZ95* / Histone-lysine N-methyltransferase NSD3 *ENSDARG0000006276519
nsd1b / nuclear receptor binding SET domain protein 1b / NSD1* / Q96L73* / nuclear receptor binding SET domain protein 1*ENSDARG0000006070519
nsd2 / nuclear receptor binding SET domain protein 2 / O96028* / Q8BVE8* / Histone-lysine N-methyltransferase NSD2 *ENSDARG0000002622518
setbp1 / SET binding protein 1 / Q9Y6X0* / Q9Z180* / SET-binding protein *ENSDARG000000937999
ezh1 / enhancer of zeste 1 polycomb repressive complex 2 subunitENSDARG000000378940


Protein motifs (from Interpro)
Interpro ID Name
 IPR000953  Chromo/chromo shadow domain
 IPR001214  SET domain
 IPR007728  Pre-SET domain
 IPR011381  Histone H3-K9 methyltransferase
 IPR016197  Chromo-like domain superfamily
 IPR023779  Chromo domain, conserved site
 IPR023780  Chromo domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006325 chromatin organization IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0031017 exocrine pancreas development IMP
 biological_processGO:0032259 methylation IEA
 biological_processGO:0034968 histone lysine methylation IEA
 biological_processGO:0051567 histone H3-K9 methylation IMP
 biological_processGO:0060042 retina morphogenesis in camera-type eye IMP
 cellular_componentGO:0000775 chromosome, centromeric region IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005694 chromosome IEA
 molecular_functionGO:0008168 methyltransferase activity IEA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0018024 histone-lysine N-methyltransferase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
SIRT1 negatively regulates rRNA expression


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000054 pericardium pericardium edematous , abnormal
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 ZFA:0000144 retinal pigmented epithelium retinal pigmented epithelium dorsal region aplastic , abnormal
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 ZFA:0001117 post-vent region post-vent region curved ventral , abnormal
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 ZFA:0001249 exocrine pancreas exocrine pancreas undifferentiated , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000068064 sirt1 / sirtuin 1 / Q96EB6*  / complex / reaction
 ENSDARG00000105345 zgc:173552  / complex / reaction
 ENSDARG00000105359 Q4QRF4 / FP325123.1 / Histone H3.2   / complex / reaction
 ENSDARG00000068436 Q6PI20 / h3f3b.1 / H3 histone, family 3B.1 / H3F3B* / H3F3C* / P84243* / Q6NXT2* / H3 histone family member 3C* / H3 histone family member 3B*  / complex / reaction
 ENSDARG00000071652 rrp8 / ribosomal RNA processing 8, methyltransferase, homolog (yeast) / O43159* / Q9DB85* / ribosomal RNA processing 8* / Ribosomal RNA-processing protein 8 *  / complex / reaction






 

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