ENSDARG00000099021


Danio rerio

Features
Gene ID: ENSDARG00000099021
  
Biological name :setdb1b
  
Synonyms : setdb1b / SET domain, bifurcated 1b
  
Possible biological names infered from orthology : Q15047 / SETDB1 / SET domain bifurcated 1
  
Species: Danio rerio
  
Chr. number: 16
Strand: -1
Band:
Gene start: 21891811
Gene end: 21917361
  
Corresponding Affymetrix probe sets: Dr.520.1.A1_at (Zebrafish Array)   NM_001077277_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000136505
Ensembl peptide - ENSDARP00000140486
Ensembl peptide - ENSDARP00000140273
Ensembl peptide - ENSDARP00000140198
NCBI entrez gene - 768131     See in Manteia.
RefSeq - NM_001077277
RefSeq - XM_005158013
RefSeq - XM_005158016
RefSeq Peptide - NP_001070745
swissprot - B2GRL9
swissprot - A0A0R4IUJ3
swissprot - A0A0R4IT84
swissprot - A0A0R4IPA3
ZFIN ID - ZDB-GENE-061013-224
Ensembl - ENSDARG00000099021
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 SETDB1ENSGALG00000024051Gallus gallus
 Q15047ENSG00000143379Homo sapiens
 Setdb1ENSMUSG00000015697Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q1L8U8 / setdb1a / SET domain, bifurcated 1aENSDARG0000004124338
ehmt1b / euchromatic histone-lysine N-methyltransferase 1b / EHMT1* / Q5DW34* / Q9H9B1* / Histone-lysine N-methyltransferase EHMT1 * / euchromatic histone lysine methyltransferase 1*ENSDARG0000002663412
ehmt1a / euchromatic histone-lysine N-methyltransferase 1a / EHMT1* / Q5DW34* / Q9H9B1* / Histone-lysine N-methyltransferase EHMT1 * / euchromatic histone lysine methyltransferase 1*ENSDARG0000006815712
ehmt2 / euchromatic histone-lysine N-methyltransferase 2 / Q96KQ7* / euchromatic histone lysine methyltransferase 2*ENSDARG0000010232511
nsd2 / nuclear receptor binding SET domain protein 2 / O96028* / Q8BVE8* / Histone-lysine N-methyltransferase NSD2 *ENSDARG000000262259
Q6DGD3 / suv39h1a / suppressor of variegation 3-9 homolog 1a / O54864* / O43463* / SUV39H1* / suppressor of variegation 3-9 1* / suppressor of variegation 3-9 homolog 1*ENSDARG000000267999
nsd3 / nuclear receptor binding SET domain protein 3 / Q6P2L6* / Q9BZ95* / Histone-lysine N-methyltransferase NSD3 *ENSDARG000000627659
nsd1a / nuclear receptor binding SET domain protein 1a / NSD1* / Q96L73* / nuclear receptor binding SET domain protein 1*ENSDARG000000600169
ash1l / ash1 (absent, small, or homeotic)-like (Drosophila) / Q99MY8* / Q9NR48* / Histone-lysine N-methyltransferase ASH1L * / ASH1 like histone lysine methyltransferase*ENSDARG000000709818
setd2 / SET domain containing 2 / E9Q5F9* / Q9BYW2* / Histone-lysine N-methyltransferase SETD2 *ENSDARG000000622448
suv39h1b / suppressor of variegation 3-9 homolog 1b / O54864* / O43463* / SUV39H1* / suppressor of variegation 3-9 1* / suppressor of variegation 3-9 homolog 1*ENSDARG000000557538
ezh2 / enhancer of zeste 2 polycomb repressive complex 2 subunit / Q15910* / Q61188* / Histone-lysine N-methyltransferase EZH2 *ENSDARG000000105718
nsd1b / nuclear receptor binding SET domain protein 1b / NSD1* / Q96L73* / nuclear receptor binding SET domain protein 1*ENSDARG000000607058
setmar / SET domain and mariner transposase fusion gene / Q53H47* / Q80UJ9* / Histone-lysine N-methyltransferase SETMAR *ENSDARG000000748366
setbp1 / SET binding protein 1 / Q9Y6X0* / Q9Z180* / SET-binding protein *ENSDARG000000937996
ezh1 / enhancer of zeste 1 polycomb repressive complex 2 subunitENSDARG000000378941


Protein motifs (from Interpro)
Interpro ID Name
 IPR001214  SET domain
 IPR001739  Methyl-CpG DNA binding
 IPR002999  Tudor domain
 IPR003616  Post-SET domain
 IPR007728  Pre-SET domain
 IPR016177  DNA-binding domain superfamily
 IPR025796  Histone-lysine N-methyltransferase SETDB1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0032259 methylation IEA
 biological_processGO:0034968 histone lysine methylation IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005694 chromosome IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0008168 methyltransferase activity IEA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0018024 histone-lysine N-methyltransferase activity IEA


Pathways (from Reactome)
Pathway description
PKMTs methylate histone lysines


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000069619 atf7ip / A0JME2 / activating transcription factor 7 interacting protein / Q7TT18* / Q3UL97* / Q5U623* / Q6VMQ6* / ATF7IP2* / activating transcription factor 7 interacting protein 2* / Activ...  / complex / reaction






 

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