ENSDARG00000055753


Danio rerio

Features
Gene ID: ENSDARG00000055753
  
Biological name :suv39h1b
  
Synonyms : suppressor of variegation 3-9 homolog 1b / suv39h1b
  
Possible biological names infered from orthology : O43463 / O54864 / suppressor of variegation 3-9 1 / suppressor of variegation 3-9 homolog 1 / SUV39H1
  
Species: Danio rerio
  
Chr. number: 8
Strand: -1
Band:
Gene start: 25750963
Gene end: 25771474
  
Corresponding Affymetrix probe sets: Dr.1811.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000149535
Ensembl peptide - ENSDARP00000072614
NCBI entrez gene - 326906     See in Manteia.
RefSeq - NM_001126482
RefSeq Peptide - NP_001119954
swissprot - B0S6M0
ZFIN ID - ZDB-GENE-030131-5105
Ensembl - ENSDARG00000055753
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 O43463ENSG00000101945Homo sapiens
 O54864ENSMUSG00000039231Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q6DGD3 / suv39h1a / suppressor of variegation 3-9 homolog 1a / O54864* / O43463* / SUV39H1* / suppressor of variegation 3-9 1* / suppressor of variegation 3-9 homolog 1*ENSDARG0000002679962
ehmt1b / euchromatic histone-lysine N-methyltransferase 1b / EHMT1* / Q5DW34* / Q9H9B1* / Histone-lysine N-methyltransferase EHMT1 * / euchromatic histone lysine methyltransferase 1*ENSDARG0000002663425
ehmt1a / euchromatic histone-lysine N-methyltransferase 1a / EHMT1* / Q5DW34* / Q9H9B1* / Histone-lysine N-methyltransferase EHMT1 * / euchromatic histone lysine methyltransferase 1*ENSDARG0000006815725
setdb1b / SET domain, bifurcated 1b / Q15047* / SETDB1* / SET domain bifurcated 1*ENSDARG0000009902124
ehmt2 / euchromatic histone-lysine N-methyltransferase 2 / Q96KQ7* / euchromatic histone lysine methyltransferase 2*ENSDARG0000010232523
Q1L8U8 / setdb1a / SET domain, bifurcated 1aENSDARG0000004124322
setd2 / SET domain containing 2 / E9Q5F9* / Q9BYW2* / Histone-lysine N-methyltransferase SETD2 *ENSDARG0000006224421
nsd1a / nuclear receptor binding SET domain protein 1a / NSD1* / Q96L73* / nuclear receptor binding SET domain protein 1*ENSDARG0000006001620
ash1l / ash1 (absent, small, or homeotic)-like (Drosophila) / Q99MY8* / Q9NR48* / Histone-lysine N-methyltransferase ASH1L * / ASH1 like histone lysine methyltransferase*ENSDARG0000007098120
setmar / SET domain and mariner transposase fusion gene / Q53H47* / Q80UJ9* / Histone-lysine N-methyltransferase SETMAR *ENSDARG0000007483620
ezh2 / enhancer of zeste 2 polycomb repressive complex 2 subunit / Q15910* / Q61188* / Histone-lysine N-methyltransferase EZH2 *ENSDARG0000001057120
nsd1b / nuclear receptor binding SET domain protein 1b / NSD1* / Q96L73* / nuclear receptor binding SET domain protein 1*ENSDARG0000006070519
nsd3 / nuclear receptor binding SET domain protein 3 / Q6P2L6* / Q9BZ95* / Histone-lysine N-methyltransferase NSD3 *ENSDARG0000006276518
nsd2 / nuclear receptor binding SET domain protein 2 / O96028* / Q8BVE8* / Histone-lysine N-methyltransferase NSD2 *ENSDARG0000002622518
setbp1 / SET binding protein 1 / Q9Y6X0* / Q9Z180* / SET-binding protein *ENSDARG0000009379910
ezh1 / enhancer of zeste 1 polycomb repressive complex 2 subunitENSDARG000000378941


Protein motifs (from Interpro)
Interpro ID Name
 IPR000953  Chromo/chromo shadow domain
 IPR001214  SET domain
 IPR003616  Post-SET domain
 IPR007728  Pre-SET domain
 IPR011381  Histone H3-K9 methyltransferase
 IPR016197  Chromo-like domain superfamily
 IPR023779  Chromo domain, conserved site
 IPR023780  Chromo domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002244 hematopoietic progenitor cell differentiation IMP
 biological_processGO:0032259 methylation IEA
 biological_processGO:0034968 histone lysine methylation IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005694 chromosome IEA
 molecular_functionGO:0008168 methyltransferase activity IEA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0018024 histone-lysine N-methyltransferase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
SIRT1 negatively regulates rRNA expression


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000105345 zgc:173552  / reaction / complex
 ENSDARG00000105359 Q4QRF4 / FP325123.1 / Histone H3.2   / complex / reaction
 ENSDARG00000068064 sirt1 / sirtuin 1 / Q96EB6*  / complex / reaction
 ENSDARG00000068436 Q6PI20 / h3f3b.1 / H3 histone, family 3B.1 / H3F3B* / H3F3C* / P84243* / Q6NXT2* / H3 histone family member 3C* / H3 histone family member 3B*  / reaction / complex
 ENSDARG00000071652 rrp8 / ribosomal RNA processing 8, methyltransferase, homolog (yeast) / O43159* / Q9DB85* / ribosomal RNA processing 8* / Ribosomal RNA-processing protein 8 *  / reaction / complex






 

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