ENSDARG00000071684


Danio rerio

Features
Gene ID: ENSDARG00000071684
  
Biological name :rx1
  
Synonyms : retinal homeobox gene 1 / rx1
  
Possible biological names infered from orthology : Q96IS3 / RAX2 / retina and anterior neural fold homeobox 2
  
Species: Danio rerio
  
Chr. number: 22
Strand: -1
Band:
Gene start: 4997784
Gene end: 5006801
  
Corresponding Affymetrix probe sets: Dr.538.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000096944
Ensembl peptide - ENSDARP00000146609
NCBI entrez gene - 30472     See in Manteia.
RefSeq - NM_131225
RefSeq Peptide - NP_571300
swissprot - Q6P984
ZFIN ID - ZDB-GENE-990415-236
Ensembl - ENSDARG00000071684
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 RAX2ENSGALG00000013431Gallus gallus
 RAX2ENSG00000173976Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
rx2 / retinal homeobox gene 2 / RAX2* / Q96IS3* / retina and anterior neural fold homeobox 2*ENSDARG0000004032172
rx3 / retinal homeobox gene 3 / RAX* / Q9Y2V3* / O35602* / Retinal homeobox protein Rx * / retina and anterior neural fold homeobox*ENSDARG0000005289343
arxa / O42115 / aristaless related homeobox a / ARX* / Q96QS3* / O35085* / Homeobox protein ARX * / aristaless related homeobox*ENSDARG0000005801127
arxb / aristaless related homeobox b / ARX* / Q96QS3* / aristaless related homeobox*ENSDARG0000010152325
alx4a / ALX homeobox 4a / ALX4* / O35137* / Q9H161* / ALX homeobox 4* / Homeobox protein aristaless-like 4 *ENSDARG0000008833224
alx4b / ALX homeobox 4b / ALX4* / O35137* / Q9H161* / ALX homeobox 4* / Homeobox protein aristaless-like 4 *ENSDARG0000007444223
vsx2 / visual system homeobox 2ENSDARG0000000557423
alx1 / Q1LVQ7 / ALX homeobox 1 / Q15699* / Q8C8B0* / ALX homeobox protein 1 *ENSDARG0000006282422
drgx / dorsal root ganglia homeobox / A6NNA5* / Prrxl1* / Q8BYH0* / paired related homeobox protein-like 1*ENSDARG0000006932920
vsx1 / visual system homeobox 1 homolog, chx10-like / Q91V10* / Q9NZR4* / visual system homeobox 1*ENSDARG0000005629220
phox2bb / paired-like homeobox 2bb / Q99453* / O35690* / PHOX2B* / paired like homeobox 2b* / Paired mesoderm homeobox protein 2B *ENSDARG0000009102919
uncx / UNC homeobox / A6NJT0* / O08934*ENSDARG0000010297619
phox2a / paired-like homeobox 2a / O14813* / Q62066* / Paired mesoderm homeobox protein 2A *ENSDARG0000000740619
uncx4.1 / Unc4.1 homeobox (C. elegans) / UNCX* / A6NJT0* / O08934* / UNC homeobox*ENSDARG0000003776018
phox2ba / paired-like homeobox 2baENSDARG0000007533015
si:dkey-43p13.5ENSDARG0000010419915


Protein motifs (from Interpro)
Interpro ID Name
 IPR001356  Homeobox domain
 IPR003654  OAR domain
 IPR009057  Homeobox-like domain superfamily
 IPR017970  Homeobox, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006366 transcription by RNA polymerase II IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0007601 visual perception IEA
 biological_processGO:0043010 camera-type eye development IEA
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000152 retina retina decreased size , abnormal
retina apoptotic , abnormal
retina lacks all parts of type Muller cell , abnormal
Show

 ZFA:0001464 retinal outer nuclear layer retinal outer nuclear layer decreased thickness , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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