ENSDARG00000007406


Danio rerio

Features
Gene ID: ENSDARG00000007406
  
Biological name :phox2a
  
Synonyms : paired-like homeobox 2a / phox2a
  
Possible biological names infered from orthology : O14813 / Paired mesoderm homeobox protein 2A / Q62066
  
Species: Danio rerio
  
Chr. number: 15
Strand: 1
Band:
Gene start: 47440477
Gene end: 47449248
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000013072
NCBI entrez gene - 404602     See in Manteia.
RefSeq - XM_005169636
swissprot - F1RCT9
ZFIN ID - ZDB-GENE-000223-14
Ensembl - ENSDARG00000007406
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 O14813ENSG00000165462Homo sapiens
 Phox2aENSMUSG00000007946Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
phox2bb / paired-like homeobox 2bb / Q99453* / O35690* / PHOX2B* / paired like homeobox 2b* / Paired mesoderm homeobox protein 2B *ENSDARG0000009102953
phox2ba / paired-like homeobox 2baENSDARG0000007533028
arxa / O42115 / aristaless related homeobox a / ARX* / Q96QS3* / O35085* / Homeobox protein ARX * / aristaless related homeobox*ENSDARG0000005801127
alx4a / ALX homeobox 4a / ALX4* / O35137* / Q9H161* / ALX homeobox 4* / Homeobox protein aristaless-like 4 *ENSDARG0000008833226
alx4b / ALX homeobox 4b / ALX4* / O35137* / Q9H161* / ALX homeobox 4* / Homeobox protein aristaless-like 4 *ENSDARG0000007444225
arxb / aristaless related homeobox b / ARX* / Q96QS3* / aristaless related homeobox*ENSDARG0000010152324
rx1 / retinal homeobox gene 1 / RAX2* / Q96IS3* / retina and anterior neural fold homeobox 2*ENSDARG0000007168423
uncx4.1 / Unc4.1 homeobox (C. elegans) / UNCX* / A6NJT0* / O08934* / UNC homeobox*ENSDARG0000003776023
alx1 / Q1LVQ7 / ALX homeobox 1 / Q15699* / Q8C8B0* / ALX homeobox protein 1 *ENSDARG0000006282423
drgx / dorsal root ganglia homeobox / A6NNA5* / Prrxl1* / Q8BYH0* / paired related homeobox protein-like 1*ENSDARG0000006932922
vsx2 / visual system homeobox 2ENSDARG0000000557422
rx3 / retinal homeobox gene 3 / RAX* / Q9Y2V3* / O35602* / Retinal homeobox protein Rx * / retina and anterior neural fold homeobox*ENSDARG0000005289322
rx2 / retinal homeobox gene 2 / RAX2* / Q96IS3* / retina and anterior neural fold homeobox 2*ENSDARG0000004032121
vsx1 / visual system homeobox 1 homolog, chx10-like / Q91V10* / Q9NZR4* / visual system homeobox 1*ENSDARG0000005629221
uncx / UNC homeobox / A6NJT0* / O08934*ENSDARG0000010297621
si:dkey-43p13.5ENSDARG0000010419920


Protein motifs (from Interpro)
Interpro ID Name
 IPR001356  Homeobox domain
 IPR009057  Homeobox-like domain superfamily
 IPR017970  Homeobox, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0003358 noradrenergic neuron development IMP
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0007420 brain development IGI
 biological_processGO:0021703 locus ceruleus development IMP
 biological_processGO:0048666 neuron development IMP
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000013 cranial ganglion cranial ganglion decreased size , abnormal
Show

 ZFA:0000107 eye eye displaced , abnormal
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 ZFA:0000396 nervous system nervous system quality , abnormal
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 ZFA:0000450 trochlear motor nucleus trochlear motor nucleus decreased size , abnormal
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 ZFA:0000539 locus coeruleus locus coeruleus lacks parts or has fewer parts of type neuron , abnormal
locus coeruleus neuron absent , abnormal
Show

 ZFA:0000553 oculomotor nucleus oculomotor nucleus decreased size , abnormal
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 ZFA:0001094 whole organism whole organism dead , abnormal
Show

 ZFA:0001306 pharyngeal arch pharyngeal arch norepinephrine secreting cell absent , abnormal
pharyngeal arch has fewer parts of type neuron , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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