ENSDARG00000058011


Danio rerio

Features
Gene ID: ENSDARG00000058011
  
Biological name :arxa
  
Synonyms : aristaless related homeobox a / arxa / O42115
  
Possible biological names infered from orthology : aristaless related homeobox / ARX / Homeobox protein ARX / O35085 / Q96QS3
  
Species: Danio rerio
  
Chr. number: 24
Strand: -1
Band:
Gene start: 23936829
Gene end: 23942722
  
Corresponding Affymetrix probe sets: Dr.9011.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000075256
NCBI entrez gene - 30657     See in Manteia.
RefSeq - NM_131384
RefSeq Peptide - NP_571459
swissprot - B3DKI9
swissprot - O42115
ZFIN ID - ZDB-GENE-990415-15
Ensembl - ENSDARG00000058011
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ARXENSGALG00000042604Gallus gallus
 ARXENSG00000004848Homo sapiens
 ArxENSMUSG00000035277Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
arxb / aristaless related homeobox b / ARX* / Q96QS3* / aristaless related homeobox*ENSDARG0000010152349
alx4b / ALX homeobox 4b / ALX4* / O35137* / Q9H161* / ALX homeobox 4* / Homeobox protein aristaless-like 4 *ENSDARG0000007444222
alx4a / ALX homeobox 4a / ALX4* / O35137* / Q9H161* / ALX homeobox 4* / Homeobox protein aristaless-like 4 *ENSDARG0000008833222
vsx2 / visual system homeobox 2ENSDARG0000000557420
rx1 / retinal homeobox gene 1 / RAX2* / Q96IS3* / retina and anterior neural fold homeobox 2*ENSDARG0000007168420
alx1 / Q1LVQ7 / ALX homeobox 1 / Q15699* / Q8C8B0* / ALX homeobox protein 1 *ENSDARG0000006282420
rx2 / retinal homeobox gene 2 / RAX2* / Q96IS3* / retina and anterior neural fold homeobox 2*ENSDARG0000004032119
rx3 / retinal homeobox gene 3 / RAX* / Q9Y2V3* / O35602* / Retinal homeobox protein Rx * / retina and anterior neural fold homeobox*ENSDARG0000005289319
drgx / dorsal root ganglia homeobox / A6NNA5* / Prrxl1* / Q8BYH0* / paired related homeobox protein-like 1*ENSDARG0000006932918
phox2bb / paired-like homeobox 2bb / Q99453* / O35690* / PHOX2B* / paired like homeobox 2b* / Paired mesoderm homeobox protein 2B *ENSDARG0000009102917
phox2a / paired-like homeobox 2a / O14813* / Q62066* / Paired mesoderm homeobox protein 2A *ENSDARG0000000740617
uncx4.1 / Unc4.1 homeobox (C. elegans) / UNCX* / A6NJT0* / O08934* / UNC homeobox*ENSDARG0000003776016
uncx / UNC homeobox / A6NJT0* / O08934*ENSDARG0000010297615
vsx1 / visual system homeobox 1 homolog, chx10-like / Q91V10* / Q9NZR4* / visual system homeobox 1*ENSDARG0000005629215
si:dkey-43p13.5ENSDARG0000010419913
phox2ba / paired-like homeobox 2baENSDARG0000007533013


Protein motifs (from Interpro)
Interpro ID Name
 IPR001356  Homeobox domain
 IPR003654  OAR domain
 IPR009057  Homeobox-like domain superfamily
 IPR017970  Homeobox, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0003322 pancreatic A cell development IMP
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0021539 subthalamus development IMP
 biological_processGO:0048666 neuron development IMP
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000458 ventral thalamus ventral thalamus dopaminergic neuron decreased amount , abnormal
Show

 ZFA:0000470 preoptic area preoptic area dopaminergic neuron decreased amount , abnormal
Show

 ZFA:0009102 pancreatic B cell pancreatic B cell regeneration increased occurrence , abnormal
Show

 ZFA:0009103 glucagon secreting cell glucagon secreting cell decreased amount , abnormal
glucagon secreting cell absent , abnormal
Show

 ZFA:0009104 pancreatic A cell pancreatic A cell decreased amount , abnormal
pancreatic A cell absent , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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