ENSDARG00000074335


Danio rerio

Features
Gene ID: ENSDARG00000074335
  
Biological name :boc
  
Synonyms : boc / BOC cell adhesion associated, oncogene regulated
  
Possible biological names infered from orthology : Q9BWV1
  
Species: Danio rerio
  
Chr. number: 24
Strand: -1
Band:
Gene start: 21206243
Gene end: 21258945
  
Corresponding Affymetrix probe sets: Dr.15669.1.S1_at (Zebrafish Array)   Dr.15997.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000098383
swissprot - F1QGR0
ZFIN ID - ZDB-GENE-030131-6560
Ensembl - ENSDARG00000074335
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 BOCENSGALG00000015152Gallus gallus
 BOCENSG00000144857Homo sapiens
 BocENSMUSG00000022687Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
cdon / cell adhesion associated, oncogene regulated / Q32MD9* / Q4KMG0* / Cell adhesion molecule-related/down-regulated by oncos *ENSDARG0000006132836
robo1 / roundabout, axon guidance receptor, homolog 1 (Drosophila) / Q9Y6N7* / roundabout guidance receptor 1*ENSDARG0000002678419
robo3 / roundabout, axon guidance receptor, homolog 3 (Drosophila) / Q96MS0* / roundabout guidance receptor 3*ENSDARG0000000564519
robo2 / roundabout, axon guidance receptor, homolog 2 (Drosophila)ENSDARG0000001489116
ncam1b / neural cell adhesion molecule 1b / NCAM1* / P13591* / neural cell adhesion molecule 1* / neural cell adhesion molecule 1 isoform 3 *ENSDARG0000000722014
ncam2 / neural cell adhesion molecule 2 / O15394* / O35136*ENSDARG0000001746613
robo4 / roundabout, axon guidance receptor, homolog 4 (Drosophila) / Q8WZ75* / roundabout guidance receptor 4*ENSDARG0000000938713
ncam1a / neural cell adhesion molecule 1a / NCAM1* / P13591* / neural cell adhesion molecule 1* / neural cell adhesion molecule 1 isoform 3 *ENSDARG0000005618113
ncam3 / neural cell adhesion molecule 3ENSDARG0000008958612
BX908388.2ENSDARG000001137747
robo2 / roundabout, axon guidance receptor, homolog 2 (Drosophila)ENSDARG000000783663
zgc:77784 / ROBO3* / Q96MS0* / roundabout guidance receptor 3*ENSDARG000000426463


Protein motifs (from Interpro)
Interpro ID Name
 IPR003598  Immunoglobulin subtype 2
 IPR003599  Immunoglobulin subtype
 IPR003961  Fibronectin type III
 IPR007110  Immunoglobulin-like domain
 IPR013098  Immunoglobulin I-set
 IPR013783  Immunoglobulin-like fold
 IPR032982  Brother of CDO


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007224 smoothened signaling pathway IEA
 biological_processGO:0007411 axon guidance IMP
 biological_processGO:0008589 regulation of smoothened signaling pathway IMP
 biological_processGO:0031290 retinal ganglion cell axon guidance IMP
 biological_processGO:0045663 positive regulation of myoblast differentiation IEA
 cellular_componentGO:0005887 integral component of plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0042802 identical protein binding IDA


Pathways (from Reactome)
Pathway description
CDO in myogenesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000059 postoptic commissure postoptic commissure absent , abnormal
postoptic commissure aplastic , abnormal
Show

 ZFA:0000101 diencephalon diencephalon glial cell mislocalised , abnormal
Show

 ZFA:0000109 forebrain forebrain physical object quality , abnormal
Show

 ZFA:0000128 midbrain midbrain ventral region physical object quality , abnormal
Show

 ZFA:0000320 caudal commissure caudal commissure defasciculated , abnormal
caudal commissure axon mislocalised , abnormal
Show

 ZFA:0000435 cranial nerve II cranial nerve II misrouted , abnormal
cranial nerve II decreased length , abnormal
Show

 ZFA:0001094 whole organism whole organism lethal (sensu genetics) , abnormal
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 ZFA:0001115 trunk trunk curved ventral , abnormal
Show

 ZFA:0001117 post-vent region post-vent region curved ventral , abnormal
Show

 ZFA:0001256 lateral floor plate lateral floor plate physical object quality , abnormal
Show

 ZFA:0001273 ventral mandibular arch ventral mandibular arch increased width , abnormal
ventral mandibular arch malformed , abnormal
Show

 ZFA:0001282 adenohypophysis adenohypophysis physical object quality , abnormal
Show

 ZFA:0001321 neurocranial trabecula neurocranial trabecula malformed , abnormal
Show

 ZFA:0001322 dorsoventral diencephalic tract dorsoventral diencephalic tract morphology , abnormal
Show

 ZFA:0001366 tract of the postoptic commissure tract of the postoptic commissure axon mislocalised laterally , abnormal
Show

 ZFA:0009116 slow muscle cell slow muscle cell decreased amount , abnormal
Show

 ZFA:0009310 retinal ganglion cell retinal ganglion cell axon misrouted , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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