ENSDARG00000074419


Danio rerio

Features
Gene ID: ENSDARG00000074419
  
Biological name :hcn4l
  
Synonyms : hcn4l / hyperpolarization activated cyclic nucleotide-gated potassium channel 4l
  
Possible biological names infered from orthology : HCN4 / hyperpolarization activated cyclic nucleotide gated potassium channel 4 / Q9Y3Q4
  
Species: Danio rerio
  
Chr. number: 25
Strand: -1
Band:
Gene start: 29211792
Gene end: 29316193
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000082682
Ensembl peptide - ENSDARP00000124810
swissprot - E7F3Z3
swissprot - F8W294
ZFIN ID - ZDB-GENE-110411-3
Ensembl - ENSDARG00000074419
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 HCN4ENSGALG00000001764Gallus gallus
 HCN4ENSG00000138622Homo sapiens
 Hcn4ENSMUSG00000032338Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
hcn4 / hyperpolarization activated cyclic nucleotide-gated potassium channel 4 / Q9Y3Q4*ENSDARG0000006168564
hcn2b / hyperpolarization activated cyclic nucleotide-gated potassium channel 2bENSDARG0000006166550
hcn1 / hyperpolarization activated cyclic nucleotide-gated potassium channel 1 / O60741* / O88704* / Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 *ENSDARG0000010448048
hcn3 / hyperpolarization activated cyclic nucleotide-gated potassium channel 3 / O88705* / Q9P1Z3* / Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3 *ENSDARG0000002719239
si:rp71-68n21.12ENSDARG0000007738221
CABZ01086574.1 / HCN4* / Q9Y3Q4* / hyperpolarization activated cyclic nucleotide gated potassium channel 4*ENSDARG0000011640417
cnga5 / cyclic nucleotide gated channel alpha 5 / CNGA2* / Q62398* / Q16280* / cyclic nucleotide gated channel alpha 2* / Cyclic nucleotide-gated olfactory channel *ENSDARG0000010296814
cnga3b / cyclic nucleotide gated channel alpha 3b / CNGA3* / Q16281* / Q9JJZ8* / cyclic nucleotide gated channel alpha 3* / Cyclic nucleotide-gated cation channel alpha-3 *ENSDARG0000001229714
cnga3a / cyclic nucleotide gated channel alpha 3a / CNGA3* / Q16281* / Q9JJZ8* / cyclic nucleotide gated channel alpha 3* / Cyclic nucleotide-gated cation channel alpha-3 *ENSDARG0000007072614
cnga4 / cyclic nucleotide gated channel alpha 4 / Q3UW12* / Q8IV77* / Cyclic nucleotide-gated cation channel alpha-4 *ENSDARG0000006938313
cnga1 / cyclic nucleotide gated channel alpha 1 / P29973* / P29974* / cGMP-gated cation channel alpha-1 *ENSDARG0000001212513
cnga2 / cyclic nucleotide gated channel alpha 2 / Q16280*ENSDARG0000010043613
si:dkey-22i16.2 / CNGA1* / P29973* / P29974* / cGMP-gated cation channel alpha-1 * / cyclic nucleotide gated channel alpha 1*ENSDARG0000002989813
cngb1a / cyclic nucleotide gated channel beta 1a / CNGB1* / Q14028* / cyclic nucleotide gated channel beta 1*ENSDARG0000006824212
cngb3.2 / cyclic nucleotide gated channel beta 3, tandem duplicate 2 / CNGB3* / Q9JJZ9* / Q9NQW8* / cyclic nucleotide gated channel beta 3* / Cyclic nucleotide-gated cation channel beta-3 *ENSDARG0000010136811
si:dkey-44k1.5 / CNGB1* / Q14028* / cyclic nucleotide gated channel beta 1*ENSDARG0000004210711
cngb3.1 / cyclic nucleotide gated channel beta 3, tandem duplicate 1 / CNGB3* / Q9JJZ9* / Q9NQW8* / cyclic nucleotide gated channel beta 3* / Cyclic nucleotide-gated cation channel beta-3 *ENSDARG0000010122510


Protein motifs (from Interpro)
Interpro ID Name
 IPR000595  Cyclic nucleotide-binding domain
 IPR003938  Potassium channel, voltage-dependent, EAG/ELK/ERG
 IPR005821  Ion transport domain
 IPR013621  Ion transport N-terminal
 IPR014710  RmlC-like jelly roll fold
 IPR018488  Cyclic nucleotide-binding, conserved site
 IPR018490  Cyclic nucleotide-binding-like
 IPR030173  Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002027 regulation of heart rate IEA
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006813 potassium ion transport IEA
 biological_processGO:0006814 sodium ion transport IEA
 biological_processGO:0034765 regulation of ion transmembrane transport IEA
 biological_processGO:0042391 regulation of membrane potential IBA
 biological_processGO:0055085 transmembrane transport IEA
 biological_processGO:0071805 potassium ion transmembrane transport IEA
 cellular_componentGO:0005887 integral component of plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0005216 ion channel activity IEA
 molecular_functionGO:0005244 voltage-gated ion channel activity IEA
 molecular_functionGO:0005249 voltage-gated potassium channel activity IEA
 molecular_functionGO:0005267 potassium channel activity IEA
 molecular_functionGO:0030552 cAMP binding IEA


Pathways (from Reactome)
Pathway description
HCN channels


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000074419 hcn4l / hyperpolarization activated cyclic nucleotide-gated potassium channel 4l / HCN4* / Q9Y3Q4* / hyperpolarization activated cyclic nucleotide gated potassium channel 4*  / complex






 

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