ENSDARG00000104480


Danio rerio

Features
Gene ID: ENSDARG00000104480
  
Biological name :hcn1
  
Synonyms : hcn1 / hyperpolarization activated cyclic nucleotide-gated potassium channel 1
  
Possible biological names infered from orthology : O60741 / O88704 / Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1
  
Species: Danio rerio
  
Chr. number: 21
Strand: -1
Band:
Gene start: 10253976
Gene end: 10488379
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000132440
Ensembl peptide - ENSDARP00000138452
NCBI entrez gene - 100334297     See in Manteia.
swissprot - A0A0R4IH62
swissprot - A0A0R4IRW0
ZFIN ID - ZDB-GENE-110520-1
Ensembl - ENSDARG00000104480
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 HCN1ENSGALG00000014875Gallus gallus
 HCN1ENSG00000164588Homo sapiens
 Hcn1ENSMUSG00000021730Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
hcn2b / hyperpolarization activated cyclic nucleotide-gated potassium channel 2bENSDARG0000006166559
hcn4 / hyperpolarization activated cyclic nucleotide-gated potassium channel 4 / Q9Y3Q4*ENSDARG0000006168556
hcn4l / hyperpolarization activated cyclic nucleotide-gated potassium channel 4l / HCN4* / Q9Y3Q4* / hyperpolarization activated cyclic nucleotide gated potassium channel 4*ENSDARG0000007441953
hcn3 / hyperpolarization activated cyclic nucleotide-gated potassium channel 3 / O88705* / Q9P1Z3* / Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3 *ENSDARG0000002719244
si:rp71-68n21.12ENSDARG0000007738223
CABZ01086574.1 / HCN4* / Q9Y3Q4* / hyperpolarization activated cyclic nucleotide gated potassium channel 4*ENSDARG0000011640420
cnga3a / cyclic nucleotide gated channel alpha 3a / CNGA3* / Q16281* / Q9JJZ8* / cyclic nucleotide gated channel alpha 3* / Cyclic nucleotide-gated cation channel alpha-3 *ENSDARG0000007072616
cnga5 / cyclic nucleotide gated channel alpha 5 / CNGA2* / Q62398* / Q16280* / cyclic nucleotide gated channel alpha 2* / Cyclic nucleotide-gated olfactory channel *ENSDARG0000010296815
cnga3b / cyclic nucleotide gated channel alpha 3b / CNGA3* / Q16281* / Q9JJZ8* / cyclic nucleotide gated channel alpha 3* / Cyclic nucleotide-gated cation channel alpha-3 *ENSDARG0000001229715
cnga2 / cyclic nucleotide gated channel alpha 2 / Q16280*ENSDARG0000010043615
cnga1 / cyclic nucleotide gated channel alpha 1 / P29973* / P29974* / cGMP-gated cation channel alpha-1 *ENSDARG0000001212515
cnga4 / cyclic nucleotide gated channel alpha 4 / Q3UW12* / Q8IV77* / Cyclic nucleotide-gated cation channel alpha-4 *ENSDARG0000006938314
si:dkey-22i16.2 / CNGA1* / P29973* / P29974* / cGMP-gated cation channel alpha-1 * / cyclic nucleotide gated channel alpha 1*ENSDARG0000002989814
si:dkey-44k1.5 / CNGB1* / Q14028* / cyclic nucleotide gated channel beta 1*ENSDARG0000004210713
cngb1a / cyclic nucleotide gated channel beta 1a / CNGB1* / Q14028* / cyclic nucleotide gated channel beta 1*ENSDARG0000006824213
cngb3.2 / cyclic nucleotide gated channel beta 3, tandem duplicate 2 / CNGB3* / Q9JJZ9* / Q9NQW8* / cyclic nucleotide gated channel beta 3* / Cyclic nucleotide-gated cation channel beta-3 *ENSDARG0000010136812
cngb3.1 / cyclic nucleotide gated channel beta 3, tandem duplicate 1 / CNGB3* / Q9JJZ9* / Q9NQW8* / cyclic nucleotide gated channel beta 3* / Cyclic nucleotide-gated cation channel beta-3 *ENSDARG0000010122512


Protein motifs (from Interpro)
Interpro ID Name
 IPR000595  Cyclic nucleotide-binding domain
 IPR003938  Potassium channel, voltage-dependent, EAG/ELK/ERG
 IPR005821  Ion transport domain
 IPR013621  Ion transport N-terminal
 IPR014710  RmlC-like jelly roll fold
 IPR018488  Cyclic nucleotide-binding, conserved site
 IPR018490  Cyclic nucleotide-binding-like
 IPR030169  Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002027 regulation of heart rate IEA
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006813 potassium ion transport IEA
 biological_processGO:0006814 sodium ion transport IEA
 biological_processGO:0007270 neuron-neuron synaptic transmission IMP
 biological_processGO:0034220 ion transmembrane transport IEA
 biological_processGO:0034765 regulation of ion transmembrane transport IEA
 biological_processGO:0035677 posterior lateral line neuromast hair cell development IMP
 biological_processGO:0035725 sodium ion transmembrane transport IEA
 biological_processGO:0055085 transmembrane transport IEA
 biological_processGO:0071805 potassium ion transmembrane transport IEA
 cellular_componentGO:0005887 integral component of plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0005216 ion channel activity IEA
 molecular_functionGO:0005244 voltage-gated ion channel activity IEA
 molecular_functionGO:0005249 voltage-gated potassium channel activity IEA
 molecular_functionGO:0005267 potassium channel activity IEA
 molecular_functionGO:0030552 cAMP binding IEA


Pathways (from Reactome)
Pathway description
HCN channels


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000104480 hcn1 / hyperpolarization activated cyclic nucleotide-gated potassium channel 1 / O60741* / O88704* / Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 *  / complex






 

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