ENSDARG00000079312


Danio rerio

Features
Gene ID: ENSDARG00000079312
  
Biological name :kmt2ca
  
Synonyms : kmt2ca / lysine (K)-specific methyltransferase 2Ca
  
Possible biological names infered from orthology : KMT2C / lysine methyltransferase 2C / Q8NEZ4
  
Species: Danio rerio
  
Chr. number: 24
Strand: 1
Band:
Gene start: 7336411
Gene end: 7549610
  
Corresponding Affymetrix probe sets: Dr.14840.1.A1_at (Zebrafish Array)   Dr.18611.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000149491
Ensembl peptide - ENSDARP00000153614
Ensembl peptide - ENSDARP00000115827
Ensembl peptide - ENSDARP00000121981
Ensembl peptide - ENSDARP00000137245
Ensembl peptide - ENSDARP00000148915
NCBI entrez gene - 560793     See in Manteia.
RefSeq - XM_005162547
swissprot - A0A0R4IM21
swissprot - F1Q6F2
swissprot - F1R5P1
ZFIN ID - ZDB-GENE-080520-3
Ensembl - ENSDARG00000079312
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000043738Gallus gallus
 ENSGALG00000032600Gallus gallus
 KMT2CENSG00000055609Homo sapiens
 Kmt2cENSMUSG00000038056Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
kmt2cb / lysine (K)-specific methyltransferase 2Cb / KMT2C* / Q8NEZ4* / lysine methyltransferase 2C*ENSDARG0000007556048
kmt2d / lysine (K)-specific methyltransferase 2D / O14686* / Q6PDK2* / lysine methyltransferase 2D* / Histone-lysine N-methyltransferase 2D *ENSDARG0000003706019
kmt2a / lysine (K)-specific methyltransferase 2A / P55200* / Q03164* / lysine methyltransferase 2A* / Mus musculus lysine (K)-specific methyltransferase 2A (Kmt2a), transcript variant 1, mRNA.*ENSDARG000000045379
kmt2bb / lysine (K)-specific methyltransferase 2Bb / KMT2B* / O08550* / Q9UMN6* / lysine methyltransferase 2B* / Histone-lysine N-methyltransferase 2B *ENSDARG000000606979
kmt2ba / lysine (K)-specific methyltransferase 2Ba / KMT2B* / O08550* / Q9UMN6* / lysine methyltransferase 2B* / Histone-lysine N-methyltransferase 2B *ENSDARG000000629628
setd1ba / SET domain containing 1B, a / Q9UPS6* / SETD1B* / Q8CFT2* / SET domain containing 1B* / Histone-lysine N-methyltransferase SETD1B *ENSDARG000000608476
setd1a / SET domain containing 1A / O15047* / AC149222.1*ENSDARG000000600306
setd1bb / SET domain containing 1B, bENSDARG000000772443


Protein motifs (from Interpro)
Interpro ID Name
 IPR001214  SET domain
 IPR001841  Zinc finger, RING-type
 IPR001965  Zinc finger, PHD-type
 IPR003616  Post-SET domain
 IPR003888  FY-rich, N-terminal
 IPR003889  FY-rich, C-terminal
 IPR009071  High mobility group box domain
 IPR011011  Zinc finger, FYVE/PHD-type
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR015943  WD40/YVTN repeat-like-containing domain superfamily
 IPR019787  Zinc finger, PHD-finger
 IPR034732  Extended PHD (ePHD) domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0032259 methylation IEA
 biological_processGO:0034968 histone lysine methylation IEA
 biological_processGO:0051568 histone H3-K4 methylation IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0044666 MLL3/4 complex IEA
 molecular_functionGO:0008168 methyltransferase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0018024 histone-lysine N-methyltransferase activity IEA
 molecular_functionGO:0042800 histone methyltransferase activity (H3-K4 specific) IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000054 pericardium pericardium edematous , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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