ENSDARG00000060697


Danio rerio

Features
Gene ID: ENSDARG00000060697
  
Biological name :kmt2bb
  
Synonyms : kmt2bb / lysine (K)-specific methyltransferase 2Bb
  
Possible biological names infered from orthology : Histone-lysine N-methyltransferase 2B / KMT2B / lysine methyltransferase 2B / O08550 / Q9UMN6
  
Species: Danio rerio
  
Chr. number: 15
Strand: -1
Band:
Gene start: 37457009
Gene end: 37543839
  
Corresponding Affymetrix probe sets: Dr.17114.1.A1_at (Zebrafish Array)   Dr.17114.2.S1_at (Zebrafish Array)   Dr.18652.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000123759
Ensembl peptide - ENSDARP00000147894
NCBI entrez gene - 566825     See in Manteia.
RefSeq - XM_009291876
RefSeq - XM_002664671
swissprot - F8W580
ZFIN ID - ZDB-GENE-080521-1
Ensembl - ENSDARG00000060697
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 KMT2BENSG00000272333Homo sapiens
 Kmt2bENSMUSG00000006307Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
kmt2ba / lysine (K)-specific methyltransferase 2Ba / KMT2B* / O08550* / Q9UMN6* / lysine methyltransferase 2B* / Histone-lysine N-methyltransferase 2B *ENSDARG0000006296229
kmt2a / lysine (K)-specific methyltransferase 2A / P55200* / Q03164* / lysine methyltransferase 2A* / Mus musculus lysine (K)-specific methyltransferase 2A (Kmt2a), transcript variant 1, mRNA.*ENSDARG0000000453724
kmt2ca / lysine (K)-specific methyltransferase 2Ca / KMT2C* / Q8NEZ4* / lysine methyltransferase 2C*ENSDARG0000007931212
kmt2cb / lysine (K)-specific methyltransferase 2Cb / KMT2C* / Q8NEZ4* / lysine methyltransferase 2C*ENSDARG0000007556011
kmt2d / lysine (K)-specific methyltransferase 2D / O14686* / Q6PDK2* / lysine methyltransferase 2D* / Histone-lysine N-methyltransferase 2D *ENSDARG000000370606
setd1a / SET domain containing 1A / O15047* / AC149222.1*ENSDARG000000600306
setd1ba / SET domain containing 1B, a / Q9UPS6* / SETD1B* / Q8CFT2* / SET domain containing 1B* / Histone-lysine N-methyltransferase SETD1B *ENSDARG000000608476
setd1bb / SET domain containing 1B, bENSDARG000000772443


Protein motifs (from Interpro)
Interpro ID Name
 IPR001214  SET domain
 IPR001965  Zinc finger, PHD-type
 IPR002857  Zinc finger, CXXC-type
 IPR003616  Post-SET domain
 IPR003888  FY-rich, N-terminal
 IPR003889  FY-rich, C-terminal
 IPR011011  Zinc finger, FYVE/PHD-type
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR019787  Zinc finger, PHD-finger
 IPR034732  Extended PHD (ePHD) domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0032259 methylation IEA
 biological_processGO:0034968 histone lysine methylation IEA
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0008168 methyltransferase activity IEA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0018024 histone-lysine N-methyltransferase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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