ENSDARG00000086393


Danio rerio

Features
Gene ID: ENSDARG00000086393
  
Biological name :dbx1a
  
Synonyms : dbx1a / developing brain homeobox 1a / Q9PTU1
  
Possible biological names infered from orthology : A6NMT0 / DBX1 / developing brain homeobox 1 / Homeobox protein DBX1 / P52950
  
Species: Danio rerio
  
Chr. number: 7
Strand: -1
Band:
Gene start: 17024602
Gene end: 17028015
  
Corresponding Affymetrix probe sets: Dr.8070.1.S1_at (Zebrafish Array)   NM_131158_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000023732
NCBI entrez gene - 30394     See in Manteia.
RefSeq - NM_131158
RefSeq Peptide - NP_571233
swissprot - B2GNV2
swissprot - Q9PTU1
ZFIN ID - ZDB-GENE-000128-8
Ensembl - ENSDARG00000086393
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 DBX1ENSGALG00000003965Gallus gallus
 DBX1ENSG00000109851Homo sapiens
 Dbx1ENSMUSG00000030507Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
dbx1b / developing brain homeobox 1b / DBX1* / P52950* / A6NMT0* / Homeobox protein DBX1 * / developing brain homeobox 1*ENSDARG0000000185963
hlx1 / H2.0-like homeo box 1 (Drosophila) / HLX* / Q14774* / Q61670* / H2.0 like homeobox* / H2.0-like homeobox protein *ENSDARG0000000913426
nkx6.2 / NK6 homeobox 2 / Q9C056*ENSDARG0000010473518
nkx6.1 / NK6 homeobox 1 / P78426* / Q99MA9* / Homeobox protein Nkx-6.1 *ENSDARG0000002256918
tlx3b / T cell leukemia homeobox 3bENSDARG0000001761517
barx1 / BARX homeobox 1 / Q9ER42* / Q9HBU1* / Homeobox protein BarH-like 1 *ENSDARG0000000740717
bsx / Q6R3Q6 / brain-specific homeobox / Q3C1V8* / Q810B3* / Brain-specific homeobox protein homolog *ENSDARG0000006897617
barhl2 / BarH-like homeobox 2 / Q8VIB5* / Q9NY43* / BarH-like 2 homeobox protein *ENSDARG0000010436116
tlx2 / T cell leukemia homeobox 2 / TLX1* / P31314* / T cell leukemia homeobox 1*ENSDARG0000001127316
nkx6.3 / NK6 homeobox 3 / A6NJ46* / Q3UHX8* / Homeobox protein Nkx-6.3 *ENSDARG0000006052916
barhl1b / BarH-like homeobox 1b / Q9BZE3* / P63157* / BARHL1* / BarH like homeobox 1* / BarH-like 1 homeobox protein *ENSDARG0000001901316
barx2 / BARX homeobox 2 / O08686* / Q9UMQ3* / Homeobox protein BarH-like 2 *ENSDARG0000004109816
barhl1a / BarH-like homeobox 1a / Q9BZE3* / P63157* / BARHL1* / BarH like homeobox 1* / BarH-like 1 homeobox protein *ENSDARG0000003550816
lbx2 / ladybird homeobox 2ENSDARG0000002513115
lbx1a / ladybird homeobox 1a / LBX1* / P52954* / P52955* / ladybird homeobox 1* / Transcription factor LBX1 *ENSDARG0000001832115
HHEX / hematopoietically expressed homeobox / Q03014*ENSDARG0000009823115
tlx1 / T cell leukemia homeobox 1 / P31314*ENSDARG0000000396514
lbx1b / ladybird homeobox 1b / LBX1* / P52954* / P52955* / ladybird homeobox 1* / Transcription factor LBX1 *ENSDARG0000001861113


Protein motifs (from Interpro)
Interpro ID Name
 IPR000047  Helix-turn-helix motif
 IPR001356  Homeobox domain
 IPR009057  Homeobox-like domain superfamily
 IPR017970  Homeobox, conserved site
 IPR020479  Homeobox domain, metazoa


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0021515 cell differentiation in spinal cord IGI
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000029 hindbrain hindbrain morphology , abnormal
Show

 ZFA:0000075 spinal cord spinal cord motor neuron decreased amount , abnormal
Show

 ZFA:0000778 spinal cord interneuron spinal cord interneuron decreased amount , abnormal
Show

 ZFA:0001115 trunk trunk decreased length , abnormal
Show

 ZFA:0001117 post-vent region post-vent region decreased length , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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