ENSDARG00000091253


Danio rerio

Features
Gene ID: ENSDARG00000091253
  
Biological name :smyd1b
  
Synonyms : SET and MYND domain containing 1b / smyd1b
  
Possible biological names infered from orthology : P97443 / Q8NB12 / SET and MYND domain containing 1 / SMYD1
  
Species: Danio rerio
  
Chr. number: 8
Strand: -1
Band:
Gene start: 1015243
Gene end: 1051527
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000067092
Ensembl peptide - ENSDARP00000130524
NCBI entrez gene - 569027     See in Manteia.
swissprot - Q2MJQ8
swissprot - Q2MJQ9
ZFIN ID - ZDB-GENE-060522-1
Ensembl - ENSDARG00000091253
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 SMYD1ENSGALG00000015935Gallus gallus
 SMYD1ENSG00000115593Homo sapiens
 Smyd1ENSMUSG00000055027Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
smyd1a / SET and MYND domain containing 1a / SMYD1* / P97443* / Q8NB12* / SET and MYND domain containing 1*ENSDARG0000000928056
smyd2a / SET and MYND domain containing 2a / SMYD2* / Q8R5A0* / Q9NRG4* / SET and MYND domain containing 2* / N-lysine methyltransferase SMYD2 *ENSDARG0000005515127
smyd3 / SET and MYND domain containing 3 / Q9CWR2* / Q9H7B4* / Histone-lysine N-methyltransferase SMYD3 *ENSDARG0000005805027
Q5RGL7 / smyd2b / SET and MYND domain containing 2b / SMYD2* / Q8R5A0* / Q9NRG4* / SET and MYND domain containing 2* / N-lysine methyltransferase SMYD2 *ENSDARG0000000562924


Protein motifs (from Interpro)
Interpro ID Name
 IPR001214  SET domain
 IPR002893  Zinc finger, MYND-type
 IPR011991  ArsR-like helix-turn-helix domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0014866 skeletal myofibril assembly IMP
 biological_processGO:0030239 myofibril assembly IMP
 biological_processGO:0030240 skeletal muscle thin filament assembly IMP
 biological_processGO:0030241 skeletal muscle myosin thick filament assembly IMP
 biological_processGO:0032259 methylation IEA
 biological_processGO:0045214 sarcomere organization IMP
 biological_processGO:0048769 sarcomerogenesis IMP
 biological_processGO:0051568 histone H3-K4 methylation IDA
 biological_processGO:0060047 heart contraction IMP
 biological_processGO:0071690 cardiac muscle myosin thick filament assembly IMP
 molecular_functionGO:0008168 methyltransferase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0017022 myosin binding IDA
 molecular_functionGO:0042800 histone methyltransferase activity (H3-K4 specific) IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000037 anatomical structure anatomical structure increased amount , abnormal
anatomical structure decreased amount , abnormal
Show

 ZFA:0000054 pericardium pericardium edematous , abnormal
Show

 ZFA:0000107 eye eye decreased size , abnormal
Show

 ZFA:0000114 heart heart quality , abnormal
heart non-contractile , abnormal
heart decreased size , abnormal
Show

 ZFA:0000155 somite somite increased amount , abnormal
Show

 ZFA:0001094 whole organism whole organism lethal (sensu genetics) , abnormal
whole organism viability , abnormal
whole organism decreased behavioural activity , abnormal
whole organism dead , abnormal
Show

 ZFA:0001114 head head malformed , abnormal
Show

 ZFA:0001439 anatomical system anatomical system quality , abnormal
Show

 ZFA:0005277 skeletal muscle skeletal muscle striated muscle thin filament disorganized , abnormal
skeletal muscle decreased functionality , abnormal
skeletal muscle spatial pattern , abnormal
skeletal muscle sarcomere disorganized , abnormal
skeletal muscle sarcomere organization quality , ameliorated
Show

 ZFA:0009116 slow muscle cell slow muscle cell Z disc disorganized , abnormal
slow muscle cell myosin filament disorganized , abnormal
slow muscle cell vacuole increased amount , abnormal
slow muscle cell sarcomere morphology , abnormal
slow muscle cell myofibril assembly disrupted , abnormal
Show

 ZFA:0009117 fast muscle cell fast muscle cell skeletal muscle myofibril absent , abnormal
fast muscle cell disorganized , abnormal
fast muscle cell vacuole increased amount , abnormal
fast muscle cell sarcomere absent , abnormal
fast muscle cell Z disc disorganized , abnormal
fast muscle cell M band disorganized , abnormal
fast muscle cell sarcomere organization disrupted , abnormal
fast muscle cell striated muscle myosin thick filament assembly disrupted , abnormal
fast muscle cell muscle thin filament assembly disrupted , abnormal
fast muscle cell sarcomere disorganized , abnormal
Show

 ZFA:0009316 cardiac muscle cell cardiac muscle cell Z disc disorganized , abnormal
cardiac muscle cell sarcomere absent , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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