ENSDARG00000092480


Danio rerio

Features
Gene ID: ENSDARG00000092480
  
Biological name :vegfbb
  
Synonyms : vascular endothelial growth factor Bb / vegfbb
  
Possible biological names infered from orthology : P49765 / P49766 / vascular endothelial growth factor B / VEGFB
  
Species: Danio rerio
  
Chr. number: 21
Strand: 1
Band:
Gene start: 26532789
Gene end: 26535721
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000114926
Ensembl peptide - ENSDARP00000153251
NCBI entrez gene - 100535766     See in Manteia.
swissprot - E9QDL3
ZFIN ID - ZDB-GENE-091204-285
Ensembl - ENSDARG00000092480
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 VEGFBENSG00000173511Homo sapiens
 VegfbENSMUSG00000024962Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
vegfba / vascular endothelial growth factor Ba / VEGFB* / P49765* / P49766* / vascular endothelial growth factor B*ENSDARG0000009099744
vegfab / vascular endothelial growth factor Ab / VEGFA* / P15692* / Q00731* / vascular endothelial growth factor A*ENSDARG0000003470035
CABZ01077555.1 / PGF* / P49763* / placental growth factor*ENSDARG0000011535933
pgfb / placental growth factor b / PGF* / P49764* / P49763* / placental growth factor*ENSDARG0000007676733
O73682 / vegfaa / vascular endothelial growth factor Aa / VEGFA* / Q00731* / P15692* / vascular endothelial growth factor A*ENSDARG0000010354232


Protein motifs (from Interpro)
Interpro ID Name
 IPR000072  PDGF/VEGF domain
 IPR023581  Platelet-derived growth factor, conserved site
 IPR029034  Cystine-knot cytokine


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001525 angiogenesis IBA
 biological_processGO:0001666 response to hypoxia IBA
 biological_processGO:0001938 positive regulation of endothelial cell proliferation IBA
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0045766 positive regulation of angiogenesis IBA
 biological_processGO:0048010 vascular endothelial growth factor receptor signaling pathway IBA
 biological_processGO:0050930 induction of positive chemotaxis IBA
 biological_processGO:0060754 positive regulation of mast cell chemotaxis IBA
 cellular_componentGO:0005615 extracellular space IBA
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0005172 vascular endothelial growth factor receptor binding IBA
 molecular_functionGO:0008083 growth factor activity IBA


Pathways (from Reactome)
Pathway description
Platelet degranulation
VEGF ligand-receptor interactions
VEGF binds to VEGFR leading to receptor dimerization


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000090997 vegfba / vascular endothelial growth factor Ba / VEGFB* / P49765* / P49766* / vascular endothelial growth factor B*  / complex
 ENSDARG00000019371 flt1 / fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) / P17948* / fms related tyrosine kinase 1*  / reaction / complex
 ENSDARG00000092480 vegfbb / vascular endothelial growth factor Bb / VEGFB* / P49765* / P49766* / vascular endothelial growth factor B*  / complex






 

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