ENSDARG00000093068


Danio rerio

Features
Gene ID: ENSDARG00000093068
  
Biological name :c3b.1
  
Synonyms : c3b.1 / complement component c3b, tandem duplicate 1
  
Possible biological names infered from orthology : C3 / complement C3 / Complement C3 Complement C3 beta chain C3-beta-c Complement C3 alpha chain C3a anaphylatoxin Acylation stimulating protein Complement C3b alpha chain Complement C3c alpha chain fragment 1 Complement C3dg fragment Complement C3g fragment Complement C3d fragment Complement C3f fragment Complement C3c alpha chain fragment 2 / P01024 / P01027
  
Species: Danio rerio
  
Chr. number: 22
Strand: -1
Band:
Gene start: 26180184
Gene end: 26236275
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000118396
Ensembl peptide - ENSDARP00000137422
Ensembl peptide - ENSDARP00000133112
NCBI entrez gene - 563665     See in Manteia.
swissprot - A5PMP6
swissprot - A0A0N4SU63
swissprot - A0A0N4STW3
ZFIN ID - ZDB-GENE-030131-2211
Ensembl - ENSDARG00000093068
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 C3ENSG00000125730Homo sapiens
 C3ENSMUSG00000024164Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
c3b.2 / complement component c3b, tandem duplicate 2 / C3* / P01024* / P01027* / complement C3* / Complement C3 Complement C3 beta chain C3-beta-c Complement C3 alpha chain C3a anaphylatoxi...ENSDARG0000000181894
c3a.4 / complement component c3a, duplicate 4 / C3* / P01024* / complement C3*ENSDARG0000009319834
c3a.6 / complement component c3a, duplicate 6 / C3* / P01024* / complement C3*ENSDARG0000004371934
c3a.3 / complement component c3a, duplicate 3 / C3* / P01024* / P01027* / complement C3* / Complement C3 Complement C3 beta chain C3-beta-c Complement C3 alpha chain C3a anaphylatoxin Acyla...ENSDARG0000005220734
c3a.1 / complement component c3a, duplicate 1 / C3* / P01024* / P01027* / complement C3* / Complement C3 Complement C3 beta chain C3-beta-c Complement C3 alpha chain C3a anaphylatoxin Acyla...ENSDARG0000001269434
c3a.2 / complement component c3a, duplicate 2 / C3* / P01024* / P01027* / complement C3* / Complement C3 Complement C3 beta chain C3-beta-c Complement C3 alpha chain C3a anaphylatoxin Acyla...ENSDARG0000008735934
si:dkey-8k3.2ENSDARG0000003842426
c4 / complement component 4 / C4A* / C4B* / P0C0L5* / P01029* / P0C0L4* / complement C4B (Chido blood group)* / complement C4A (Rodgers blood group)* / Complement C4-B Complement C4 beta ch...ENSDARG0000001506525
c5 / complement component 5 / P01031* / complement C5*ENSDARG0000002100424
cpamd8 / C3 and PZP-like, alpha-2-macroglobulin domain containing 8 / Q8IZJ3*ENSDARG0000005653018
zgc:165518 / A2ML1* / A8K2U0* / alpha-2-macroglobulin like 1*ENSDARG0000007573718
si:dkey-46g23.2 / A2ML1* / A8K2U0* / alpha-2-macroglobulin like 1*ENSDARG0000011581717
c3a.5 / complement component c3a, duplicate 5 / C3* / P01024* / P01027* / complement C3* / Complement C3 Complement C3 beta chain C3-beta-c Complement C3 alpha chain C3a anaphylatoxin Acyla...ENSDARG0000005346217
a2ml / alpha-2-macroglobulin-like / A2ML1* / A8K2U0* / alpha-2-macroglobulin like 1*ENSDARG0000005631417
si:ch211-212c13.10 / A2ML1* / A8K2U0* / alpha-2-macroglobulin like 1*ENSDARG0000009319917
sb:cb37 / si:dkey-105h12.2 / A2ML1 (1 of many) / A2ML1* / A8K2U0* / alpha-2-macroglobulin like 1*ENSDARG0000004164517
zgc:171446 / A2ML1* / A8K2U0* / alpha-2-macroglobulin like 1*ENSDARG0000011600517
zgc:171445 / A2ML1 (1 of many) / A2ML1* / A8K2U0* / alpha-2-macroglobulin like 1*ENSDARG0000011520517
si:dkey-105h12.2 / A2ML1 (1 of many) / A2ML1* / A8K2U0* / alpha-2-macroglobulin like 1*ENSDARG0000004168517
si:dkey-46g23.5 / A2ML1 (1 of many) / A2ML1* / A8K2U0* / alpha-2-macroglobulin like 1*ENSDARG0000000883517


Protein motifs (from Interpro)
Interpro ID Name
 IPR000020  Anaphylatoxin/fibulin
 IPR001134  Netrin domain
 IPR001599  Alpha-2-macroglobulin
 IPR002890  Alpha-2-macroglobulin, N-terminal
 IPR008930  Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid
 IPR008993  Tissue inhibitor of metalloproteinases-like, OB-fold
 IPR009048  Alpha-macroglobulin, receptor-binding
 IPR011625  Alpha-2-macroglobulin, N-terminal 2
 IPR011626  Alpha-macroglobulin complement component
 IPR013783  Immunoglobulin-like fold
 IPR018081  Anaphylatoxin, complement system
 IPR018933  Netrin module, non-TIMP type
 IPR019565  Alpha-2-macroglobulin, thiol-ester bond-forming


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006956 complement activation IEA
 biological_processGO:0010951 negative regulation of endopeptidase activity IEA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space IEA
 molecular_functionGO:0004866 endopeptidase inhibitor activity IEA


Pathways (from Reactome)
Pathway description
Alternative complement activation
Activation of C3 and C5
Peptide ligand-binding receptors
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
G alpha (i) signalling events
Neutrophil degranulation
Post-translational protein phosphorylation
Regulation of Complement cascade


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr