ENSDARG00000098237


Danio rerio

Features
Gene ID: ENSDARG00000098237
  
Biological name :fbn2b
  
Synonyms : fbn2b / fibrillin 2b
  
Possible biological names infered from orthology :
  
Species: Danio rerio
  
Chr. number: 22
Strand: -1
Band:
Gene start: 4524367
Gene end: 4649238
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000112260
Ensembl peptide - ENSDARP00000134527
NCBI entrez gene - 571786     See in Manteia.
RefSeq - NM_001135790
RefSeq Peptide - NP_001129262
swissprot - E7FG71
swissprot - A0A0G2KQ62
ZFIN ID - ZDB-GENE-090112-3
Ensembl - ENSDARG00000098237
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000037625Gallus gallus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
fbn2a / fibrillin 2a / FBN1* / FBN2* / Q61555* / P35555* / P35556* / Q61554* / fibrillin 1* / fibrillin 2* / Fibrillin-1 Asprosin* / Fibrillin-2 Fibrillin-2 C-terminal peptide*ENSDARG0000005189662
si:dkey-30j22.1ENSDARG0000004282937
si:ch73-105b23.1ENSDARG0000008755817
BX663503.3 / LTBP4* / Q8K4G1* / Q8N2S1* / latent transforming growth factor beta binding protein 4*ENSDARG0000009913715
ltbp1 / latent transforming growth factor beta binding protein 1 / Q14766* / Q8CG19*ENSDARG0000005692214
FP102018.1 / Danio rerio latent transforming growth factor beta binding protein 3 (ltbp3), mRNA. / LTBP3* / Q9NS15* / latent transforming growth factor beta binding protein 3*ENSDARG0000003568213
fbln2 / fibulin 2 / P37889* / P98095*ENSDARG0000001515610
si:dkey-235d18.5ENSDARG000000396529
FBLN1 / fibulin 1 / P23142*ENSDARG000001033116
fbln5 / fibulin 5 / Q9UBX5* / Q9WVH9*ENSDARG000000392734
efemp2a / EGF containing fibulin extracellular matrix protein 2a / EFEMP2* / O95967* / Q9WVJ9* / EGF containing fibulin extracellular matrix protein 2* / EGF-containing fibulin-like extrace...ENSDARG000000943244
efemp2b / EGF containing fibulin extracellular matrix protein 2b / EFEMP2* / O95967* / Q9WVJ9* / EGF containing fibulin extracellular matrix protein 2* / EGF-containing fibulin-like extrace...ENSDARG000000208114
si:ch73-173h19.3 / EFEMP1* / Q12805* / Q8BPB5* / EGF containing fibulin extracellular matrix protein 1* / EGF-containing fibulin-like extracellular matrix protein 1 *ENSDARG000001042103
CU570800.1 / EFEMP1* / Q12805* / EGF containing fibulin extracellular matrix protein 1*ENSDARG000000591212


Protein motifs (from Interpro)
Interpro ID Name
 IPR000152  EGF-type aspartate/asparagine hydroxylation site
 IPR000742  EGF-like domain
 IPR001881  EGF-like calcium-binding domain
 IPR009030  Growth factor receptor cysteine-rich domain superfamily
 IPR013032  EGF-like, conserved site
 IPR017878  TB domain
 IPR018097  EGF-like calcium-binding, conserved site
 IPR026823  Complement Clr-like EGF domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001570 vasculogenesis IMP
 biological_processGO:0003007 heart morphogenesis IMP
 biological_processGO:0003160 endocardium morphogenesis IGI
 biological_processGO:0003250 regulation of cell proliferation involved in heart valve morphogenesis IGI
 biological_processGO:0007155 cell adhesion IGI
 biological_processGO:0009653 anatomical structure morphogenesis IBA
 biological_processGO:0048570 notochord morphogenesis IMP
 biological_processGO:0060958 endocardial cell development IGI
 biological_processGO:0090287 regulation of cellular response to growth factor stimulus IBA
 cellular_componentGO:0031012 extracellular matrix IBA
 molecular_functionGO:0005201 extracellular matrix structural constituent IBA
 molecular_functionGO:0005509 calcium ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000009 cardiac ventricle cardiac ventricle has extra parts of type ventricular myocardium , abnormal
Show

 ZFA:0000014 dorsal aorta dorsal aorta decreased diameter , abnormal
Show

 ZFA:0000040 median fin fold median fin fold attenuate , abnormal
median fin fold blistered , abnormal
Show

 ZFA:0000054 pericardium pericardium edematous , abnormal
Show

 ZFA:0000076 swim bladder swim bladder morphology , abnormal
Show

 ZFA:0000102 dorsal fin fold dorsal fin fold erose , abnormal
Show

 ZFA:0000114 heart heart physical object quality , abnormal
heart edematous , abnormal
heart quality , abnormal
Show

 ZFA:0000135 notochord notochord kinked , abnormal
notochord morphology , abnormal
notochord delaminated , abnormal
notochord deformed , abnormal
Show

 ZFA:0000180 caudal vein caudal vein structure, cavities , abnormal
caudal vein disorganized , abnormal
caudal vein blood vessel endothelial cell disorganized , abnormal
caudal vein malformed , abnormal
Show

 ZFA:0000471 atrium atrium has fewer parts of type atrial endocardium , abnormal
atrium lacks parts or has fewer parts of type endocardium cell, abnormal
Show

 ZFA:0000477 posterior cardinal vein posterior cardinal vein decreased diameter , abnormal
Show

 ZFA:0001058 caudal fin caudal fin truncated , abnormal
caudal fin erose , abnormal
Show

 ZFA:0001069 ventral fin fold ventral fin fold hemorrhagic , abnormal
ventral fin fold increased accumulation blood cell , abnormal
ventral fin fold endothelial cell disorganized , abnormal
Show

 ZFA:0001094 whole organism whole organism lethal (sensu genetics) , abnormal
whole organism necrotic , abnormal
Show

 ZFA:0001115 trunk trunk edematous , abnormal
trunk integument distended , abnormal
Show

 ZFA:0001286 caudal vein plexus caudal vein plexus disorganized , abnormal
Show

 ZFA:0001315 atrioventricular canal atrioventricular canal cellular quality , abnormal
atrioventricular canal increased width , abnormal
Show

 ZFA:0001318 cardiac jelly cardiac jelly absent , abnormal
cardiac jelly mislocalised , abnormal
cardiac jelly decreased thickness , abnormal
Show

 ZFA:0001319 myocardium myocardium attached to endocardium , abnormal
Show

 ZFA:0001320 endocardium endocardium perforate , abnormal
endocardium porous , abnormal
endocardium cell disorganized , abnormal
endocardium cell decreased adhesivity , abnormal
Show

 ZFA:0001439 anatomical system anatomical system physical object quality , abnormal
anatomical system quality , abnormal
Show

 ZFA:0001614 atrial endocardium atrial endocardium mislocalised , abnormal
Show

 ZFA:0001616 atrioventricular canal endocardium atrioventricular canal endocardium cellular adhesivity , abnormal
Show

 ZFA:0005037 post-vent vasculature post-vent vasculature malformed , abnormal
Show

 ZFA:0005064 atrioventricular valve atrioventricular valve malformed , abnormal
Show

 ZFA:0009091 melanocyte melanocyte absent , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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