ENSDARG00000099996


Danio rerio

Features
Gene ID: ENSDARG00000099996
  
Biological name :rhot1a
  
Synonyms : Q6NVC5 / ras homolog family member T1a / rhot1a
  
Possible biological names infered from orthology : Q8BG51 / Q8IXI2 / ras homolog family member T1 / RHOT1
  
Species: Danio rerio
  
Chr. number: 3
Strand: 1
Band:
Gene start: 26288981
Gene end: 26319758
  
Corresponding Affymetrix probe sets: Dr.14651.1.A1_at (Zebrafish Array)   Dr.6639.1.S1_at (Zebrafish Array)   NM_212704_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000135168
Ensembl peptide - ENSDARP00000141563
Ensembl peptide - ENSDARP00000139254
NCBI entrez gene - 327143     See in Manteia.
RefSeq - NM_212704
RefSeq Peptide - NP_997869
swissprot - A0A0R4ISG5
swissprot - A0A0R4ILB0
swissprot - Q6NVC5
ZFIN ID - ZDB-GENE-030131-5354
Ensembl - ENSDARG00000099996
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 RHOT1ENSGALG00000003397Gallus gallus
 RHOT1ENSG00000126858Homo sapiens
 Rhot1ENSMUSG00000017686Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
rhot1b / ras homolog family member T1 / RHOT1* / Q8BG51* / Q8IXI2*ENSDARG0000010331382
rhot2 / Q32LU1 / ras homolog family member T2 / Q8IXI1* / Q8JZN7* / Gm20683*ENSDARG0000005632861


Protein motifs (from Interpro)
Interpro ID Name
 IPR001806  Small GTPase superfamily
 IPR002048  EF-hand domain
 IPR005225  Small GTP-binding protein domain
 IPR011992  EF-hand domain pair
 IPR013566  EF hand associated, type-1
 IPR013567  EF hand associated, type-2
 IPR018247  EF-Hand 1, calcium-binding site
 IPR020860  MIRO domain
 IPR021181  Mitochondrial Rho GTPase
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007005 mitochondrion organization IEA
 biological_processGO:0019725 cellular homeostasis ISS
 biological_processGO:0047497 mitochondrion transport along microtubule ISS
 biological_processGO:0097345 mitochondrial outer membrane permeabilization ISS
 cellular_componentGO:0005739 mitochondrion IDA
 cellular_componentGO:0005741 mitochondrial outer membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0031307 integral component of mitochondrial outer membrane ISS
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003924 GTPase activity IEA
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0005525 GTP binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Rho GTPase cycle
Ub-specific processing proteases


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0001094 whole organism whole organism anterior-posterior axis decreased length , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000056842 usp30 / A2BGT0 / ubiquitin specific peptidase 30 / Q3UN04* / Q70CQ3*  / complex






 

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