ENSDARG00000100515


Danio rerio

Features
Gene ID: ENSDARG00000100515
  
Biological name :dusp1
  
Synonyms : dual specificity phosphatase 1 / dusp1
  
Possible biological names infered from orthology : Dual specificity protein phosphatase 1 / P28562 / P28563
  
Species: Danio rerio
  
Chr. number: 14
Strand: -1
Band:
Gene start: 15760253
Gene end: 15763648
  
Corresponding Affymetrix probe sets: Dr.2413.1.S1_at (Zebrafish Array)   NM_213067_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000137487
NCBI entrez gene - 406340     See in Manteia.
RefSeq - NM_213067
RefSeq Peptide - NP_998232
swissprot - A0A0R4IS50
ZFIN ID - ZDB-GENE-040426-2018
Ensembl - ENSDARG00000100515
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 DUSP1ENSGALG00000040360Gallus gallus
 DUSP1ENSG00000120129Homo sapiens
 Dusp1ENSMUSG00000024190Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
dusp4 / dual specificity phosphatase 4 / Q13115* / Q8BFV3* / Dual specificity protein phosphatase 4 *ENSDARG0000004468858
dusp5 / dual specificity phosphatase 5 / Q16690*ENSDARG0000001930744
dusp2 / dual specificity phosphatase 2 / Q05923*ENSDARG0000009810841
dusp8a / dual specificity phosphatase 8a / DUSP8* / Q13202* / O09112* / dual specificity phosphatase 8* / Dual specificity protein phosphatase 8 *ENSDARG0000000929931
dusp7 / dual specificity phosphatase 7 / Q16829*ENSDARG0000010141329
dusp6 / dual specificity phosphatase 6 / Q16828* / Q9DBB1* / Dual specificity protein phosphatase 6 *ENSDARG0000007091428
dusp16 / dual specificity phosphatase 16 / Q9BY84*ENSDARG0000010247428
dusp10 / dual specificity phosphatase 10 / Q9ESS0* / Q9Y6W6* / Dual specificity protein phosphatase 10 *ENSDARG0000005246527
si:dkey-175m17.7ENSDARG0000007831724
ssh2a / slingshot protein phosphatase 2a / SSH2* / Q5SW75* / Q76I76* / slingshot protein phosphatase 2* / Protein phosphatase Slingshot homolog 2 *ENSDARG0000008844023
ssh2b / slingshot protein phosphatase 2b / SSH2* / Q5SW75* / Q76I76* / slingshot protein phosphatase 2* / Protein phosphatase Slingshot homolog 2 *ENSDARG0000009895522
ssh1a / slingshot protein phosphatase 1a / SSH1* / Q76I79* / Q8WYL5* / slingshot protein phosphatase 1* / Protein phosphatase Slingshot homolog 1 *ENSDARG0000005678021
ssh1b / slingshot protein phosphatase 1b / SSH1* / Q76I79* / Q8WYL5* / slingshot protein phosphatase 1* / Protein phosphatase Slingshot homolog 1 *ENSDARG0000001003119
si:ch211-203d1.3 / SSH3* / Q8TE77* / Q8K330* / slingshot protein phosphatase 3* / Mus musculus slingshot protein phosphatase 3 (Ssh3), transcript variant 2, mRNA.*ENSDARG0000007959119
si:ch211-195b15.8ENSDARG0000009483618


Protein motifs (from Interpro)
Interpro ID Name
 IPR000340  Dual specificity phosphatase, catalytic domain
 IPR000387  Tyrosine specific protein phosphatases domain
 IPR001763  Rhodanese-like domain
 IPR003595  Protein-tyrosine phosphatase, catalytic
 IPR008343  Mitogen-activated protein (MAP) kinase phosphatase
 IPR016130  Protein-tyrosine phosphatase, active site
 IPR020417  Atypical dual specificity phosphatase
 IPR020422  Dual specificity protein phosphatase domain
 IPR024950  Dual specificity phosphatase
 IPR029021  Protein-tyrosine phosphatase-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000188 inactivation of MAPK activity IEA
 biological_processGO:0006470 protein dephosphorylation IEA
 biological_processGO:0016311 dephosphorylation IEA
 biological_processGO:0035335 peptidyl-tyrosine dephosphorylation IEA
 molecular_functionGO:0004721 phosphoprotein phosphatase activity IEA
 molecular_functionGO:0004725 protein tyrosine phosphatase activity IEA
 molecular_functionGO:0008138 protein tyrosine/serine/threonine phosphatase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016791 phosphatase activity IEA
 molecular_functionGO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity IEA


Pathways (from Reactome)
Pathway description
RAF-independent MAPK1/3 activation
Negative regulation of MAPK pathway


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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