ENSDARG00000009299


Danio rerio

Features
Gene ID: ENSDARG00000009299
  
Biological name :dusp8a
  
Synonyms : dual specificity phosphatase 8a / dusp8a
  
Possible biological names infered from orthology : dual specificity phosphatase 8 / Dual specificity protein phosphatase 8 / DUSP8 / O09112 / Q13202
  
Species: Danio rerio
  
Chr. number: 25
Strand: -1
Band:
Gene start: 22979743
Gene end: 23052707
  
Corresponding Affymetrix probe sets: Dr.12819.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000022233
NCBI entrez gene - 393854     See in Manteia.
RefSeq - NM_200880
RefSeq Peptide - NP_957174
swissprot - F1QVZ9
ZFIN ID - ZDB-GENE-040426-1842
Ensembl - ENSDARG00000009299
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 DUSP8ENSGALG00000006647Gallus gallus
 DUSP8ENSG00000184545Homo sapiens
 Dusp8ENSMUSG00000037887Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
dusp16 / dual specificity phosphatase 16 / Q9BY84*ENSDARG0000010247441
dusp4 / dual specificity phosphatase 4 / Q13115* / Q8BFV3* / Dual specificity protein phosphatase 4 *ENSDARG0000004468819
dusp7 / dual specificity phosphatase 7 / Q16829*ENSDARG0000010141318
si:ch211-195b15.8ENSDARG0000009483618
dusp1 / dual specificity phosphatase 1 / P28562* / P28563* / Dual specificity protein phosphatase 1 *ENSDARG0000010051518
dusp6 / dual specificity phosphatase 6 / Q16828* / Q9DBB1* / Dual specificity protein phosphatase 6 *ENSDARG0000007091418
dusp10 / dual specificity phosphatase 10 / Q9ESS0* / Q9Y6W6* / Dual specificity protein phosphatase 10 *ENSDARG0000005246517
ssh2a / slingshot protein phosphatase 2a / SSH2* / Q5SW75* / Q76I76* / slingshot protein phosphatase 2* / Protein phosphatase Slingshot homolog 2 *ENSDARG0000008844016
ssh1b / slingshot protein phosphatase 1b / SSH1* / Q76I79* / Q8WYL5* / slingshot protein phosphatase 1* / Protein phosphatase Slingshot homolog 1 *ENSDARG0000001003116
ssh2b / slingshot protein phosphatase 2b / SSH2* / Q5SW75* / Q76I76* / slingshot protein phosphatase 2* / Protein phosphatase Slingshot homolog 2 *ENSDARG0000009895515
dusp5 / dual specificity phosphatase 5 / Q16690*ENSDARG0000001930715
dusp2 / dual specificity phosphatase 2 / Q05923*ENSDARG0000009810815
ssh1a / slingshot protein phosphatase 1a / SSH1* / Q76I79* / Q8WYL5* / slingshot protein phosphatase 1* / Protein phosphatase Slingshot homolog 1 *ENSDARG0000005678014
si:ch211-203d1.3 / SSH3* / Q8TE77* / Q8K330* / slingshot protein phosphatase 3* / Mus musculus slingshot protein phosphatase 3 (Ssh3), transcript variant 2, mRNA.*ENSDARG0000007959113
si:dkey-175m17.7ENSDARG0000007831713


Protein motifs (from Interpro)
Interpro ID Name
 IPR000340  Dual specificity phosphatase, catalytic domain
 IPR000387  Tyrosine specific protein phosphatases domain
 IPR001763  Rhodanese-like domain
 IPR008343  Mitogen-activated protein (MAP) kinase phosphatase
 IPR016130  Protein-tyrosine phosphatase, active site
 IPR020422  Dual specificity protein phosphatase domain
 IPR024950  Dual specificity phosphatase
 IPR029021  Protein-tyrosine phosphatase-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000188 inactivation of MAPK activity IEA
 biological_processGO:0006470 protein dephosphorylation IEA
 biological_processGO:0016311 dephosphorylation IEA
 biological_processGO:0035335 peptidyl-tyrosine dephosphorylation IEA
 molecular_functionGO:0004725 protein tyrosine phosphatase activity IEA
 molecular_functionGO:0008138 protein tyrosine/serine/threonine phosphatase activity IEA
 molecular_functionGO:0016791 phosphatase activity IEA
 molecular_functionGO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity IEA


Pathways (from Reactome)
Pathway description
RAF-independent MAPK1/3 activation
Negative regulation of MAPK pathway


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr