ENSGALG00000006647


Gallus gallus

Features
Gene ID: ENSGALG00000006647
  
Biological name :DUSP8
  
Synonyms : dual specificity phosphatase 8 / DUSP8
  
Possible biological names infered from orthology : Dual specificity protein phosphatase 8 / O09112 / Q13202
  
Species: Gallus gallus
  
Chr. number: 5
Strand: 1
Band:
Gene start: 14163587
Gene end: 14184836
  
Corresponding Affymetrix probe sets: Gga.10279.1.S1_at (Chicken Array)   Gga.17304.1.S1_at (Chicken Array)   GgaAffx.22004.3.S1_s_at (Chicken Array)   GgaAffx.4139.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000010737
NCBI entrez gene - 770435     See in Manteia.
RefSeq - XM_001232892
RefSeq - XM_015286687
RefSeq - XM_015286688
swissprot - E1C2M2
Ensembl - ENSGALG00000006647
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 dusp8aENSDARG00000009299Danio rerio
 DUSP8ENSG00000184545Homo sapiens
 Dusp8ENSMUSG00000037887Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
DUSP16* / Q9BY84* / dual specificity phosphatase 16*ENSGALG0000002815547
SSH1 / slingshot protein phosphatase 1 / Q76I79* / Q8WYL5* / Protein phosphatase Slingshot homolog 1 *ENSGALG0000000492819
SSH2 / slingshot protein phosphatase 2 / Q5SW75* / Q76I76* / Protein phosphatase Slingshot homolog 2 *ENSGALG0000002157218
DUSP6 / dual specificity protein phosphatase 6 / Q16828* / Q9DBB1* / dual specificity phosphatase 6*ENSGALG0000001120717
DUSP7 / Gallus gallus dual specificity phosphatase 7 (DUSP7), mRNA. / Q16829* / Q91Z46* / dual specificity phosphatase 7* / Dual specificity protein phosphatase 7 *ENSGALG0000004165017
DUSP1 / dual specificity phosphatase 1 / P28562* / P28563* / Dual specificity protein phosphatase 1 *ENSGALG0000004036017
DUSP4 / dual specificity protein phosphatase 4 / Q13115* / Q8BFV3* / dual specificity phosphatase 4*ENSGALG0000001141917
DUSP10 / dual specificity protein phosphatase 10 / Q9ESS0* / Q9Y6W6* / dual specificity phosphatase 10*ENSGALG0000000945016
DUSP5 / dual specificity phosphatase 5 / Q16690*ENSGALG0000003261816


Protein motifs (from Interpro)
Interpro ID Name
 IPR000340  Dual specificity phosphatase, catalytic domain
 IPR000387  Tyrosine specific protein phosphatases domain
 IPR001763  Rhodanese-like domain
 IPR008343  Mitogen-activated protein (MAP) kinase phosphatase
 IPR016130  Protein-tyrosine phosphatase, active site
 IPR020422  Dual specificity protein phosphatase domain
 IPR024950  Dual specificity phosphatase
 IPR029021  Protein-tyrosine phosphatase-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000188 inactivation of MAPK activity IEA
 biological_processGO:0006470 protein dephosphorylation IEA
 biological_processGO:0016311 dephosphorylation IEA
 biological_processGO:0035335 peptidyl-tyrosine dephosphorylation IEA
 molecular_functionGO:0004725 protein tyrosine phosphatase activity IEA
 molecular_functionGO:0008138 protein tyrosine/serine/threonine phosphatase activity IEA
 molecular_functionGO:0016791 phosphatase activity IEA
 molecular_functionGO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity IEA


Pathways (from Reactome)
Pathway description
RAF-independent MAPK1/3 activation
Negative regulation of MAPK pathway


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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