ENSGALG00000041650


Gallus gallus

Features
Gene ID: ENSGALG00000041650
  
Biological name :DUSP7
  
Synonyms : DUSP7 / Gallus gallus dual specificity phosphatase 7 (DUSP7), mRNA.
  
Possible biological names infered from orthology : dual specificity phosphatase 7 / Dual specificity protein phosphatase 7 / Q16829 / Q91Z46
  
Species: Gallus gallus
  
Chr. number: 12
Strand: 1
Band:
Gene start: 254374
Gene end: 261731
  
Corresponding Affymetrix probe sets: Gga.2288.1.A1_at (Chicken Array)   GgaAffx.24216.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000043675
NCBI entrez gene - 415891     See in Manteia.
RefSeq - NM_001318409
RefSeq - XM_015292745
RefSeq Peptide - NP_001305338
swissprot - Q5F335
Ensembl - ENSGALG00000041650
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 dusp7ENSDARG00000101413Danio rerio
 DUSP7ENSG00000164086Homo sapiens
 Dusp7ENSMUSG00000053716Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
DUSP6 / dual specificity protein phosphatase 6 / Q16828* / Q9DBB1* / dual specificity phosphatase 6*ENSGALG0000001120774
DUSP1 / dual specificity phosphatase 1 / P28562* / P28563* / Dual specificity protein phosphatase 1 *ENSGALG0000004036031
DUSP4 / dual specificity protein phosphatase 4 / Q13115* / Q8BFV3* / dual specificity phosphatase 4*ENSGALG0000001141930
DUSP16* / Q9BY84* / dual specificity phosphatase 16*ENSGALG0000002815529
DUSP8 / dual specificity phosphatase 8 / O09112* / Q13202* / Dual specificity protein phosphatase 8 *ENSGALG0000000664729
DUSP10 / dual specificity protein phosphatase 10 / Q9ESS0* / Q9Y6W6* / dual specificity phosphatase 10*ENSGALG0000000945028
DUSP5 / dual specificity phosphatase 5 / Q16690*ENSGALG0000003261827
SSH1 / slingshot protein phosphatase 1 / Q76I79* / Q8WYL5* / Protein phosphatase Slingshot homolog 1 *ENSGALG0000000492826
SSH2 / slingshot protein phosphatase 2 / Q5SW75* / Q76I76* / Protein phosphatase Slingshot homolog 2 *ENSGALG0000002157223


Protein motifs (from Interpro)
Interpro ID Name
 IPR000340  Dual specificity phosphatase, catalytic domain
 IPR000387  Tyrosine specific protein phosphatases domain
 IPR001763  Rhodanese-like domain
 IPR008343  Mitogen-activated protein (MAP) kinase phosphatase
 IPR020422  Dual specificity protein phosphatase domain
 IPR024950  Dual specificity phosphatase
 IPR029021  Protein-tyrosine phosphatase-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000188 inactivation of MAPK activity IEA
 biological_processGO:0006470 protein dephosphorylation IEA
 biological_processGO:0016311 dephosphorylation IEA
 biological_processGO:0035335 peptidyl-tyrosine dephosphorylation IEA
 biological_processGO:0043407 negative regulation of MAP kinase activity IEA
 cellular_componentGO:0005829 cytosol IEA
 molecular_functionGO:0004721 phosphoprotein phosphatase activity IEA
 molecular_functionGO:0004725 protein tyrosine phosphatase activity IEA
 molecular_functionGO:0008138 protein tyrosine/serine/threonine phosphatase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016791 phosphatase activity IEA
 molecular_functionGO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity IEA


Pathways (from Reactome)
Pathway description
RAF-independent MAPK1/3 activation
ERKs are inactivated
Negative regulation of MAPK pathway


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000001501 MAPK1 / mitogen-activated protein kinase 1 / P28482* / P63085* / Mus musculus mitogen-activated protein kinase 1 (Mapk1), transcript variant 3, mRNA.*  / reaction






 

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