ENSGALG00000009450


Gallus gallus

Features
Gene ID: ENSGALG00000009450
  
Biological name :DUSP10
  
Synonyms : dual specificity protein phosphatase 10 / DUSP10
  
Possible biological names infered from orthology : dual specificity phosphatase 10 / Q9ESS0 / Q9Y6W6
  
Species: Gallus gallus
  
Chr. number: 3
Strand: 1
Band:
Gene start: 18335178
Gene end: 18357448
  
Corresponding Affymetrix probe sets: Gga.16879.1.S1_at (Chicken Array)   GgaAffx.12579.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000015365
NCBI entrez gene - 421340     See in Manteia.
RefSeq - NM_001031044
RefSeq Peptide - NP_001026215
swissprot - F1NXH3
Ensembl - ENSGALG00000009450
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 dusp10ENSDARG00000052465Danio rerio
 DUSP10ENSG00000143507Homo sapiens
 Dusp10ENSMUSG00000039384Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
DUSP6 / dual specificity protein phosphatase 6 / Q16828* / Q9DBB1* / dual specificity phosphatase 6*ENSGALG0000001120723
DUSP16* / Q9BY84* / dual specificity phosphatase 16*ENSGALG0000002815523
DUSP8 / dual specificity phosphatase 8 / O09112* / Q13202* / Dual specificity protein phosphatase 8 *ENSGALG0000000664722
DUSP7 / Gallus gallus dual specificity phosphatase 7 (DUSP7), mRNA. / Q16829* / Q91Z46* / dual specificity phosphatase 7* / Dual specificity protein phosphatase 7 *ENSGALG0000004165022
DUSP1 / dual specificity phosphatase 1 / P28562* / P28563* / Dual specificity protein phosphatase 1 *ENSGALG0000004036021
DUSP4 / dual specificity protein phosphatase 4 / Q13115* / Q8BFV3* / dual specificity phosphatase 4*ENSGALG0000001141921
SSH1 / slingshot protein phosphatase 1 / Q76I79* / Q8WYL5* / Protein phosphatase Slingshot homolog 1 *ENSGALG0000000492819
SSH2 / slingshot protein phosphatase 2 / Q5SW75* / Q76I76* / Protein phosphatase Slingshot homolog 2 *ENSGALG0000002157219
DUSP5 / dual specificity phosphatase 5 / Q16690*ENSGALG0000003261818


Protein motifs (from Interpro)
Interpro ID Name
 IPR000340  Dual specificity phosphatase, catalytic domain
 IPR000387  Tyrosine specific protein phosphatases domain
 IPR001763  Rhodanese-like domain
 IPR008343  Mitogen-activated protein (MAP) kinase phosphatase
 IPR016130  Protein-tyrosine phosphatase, active site
 IPR020422  Dual specificity protein phosphatase domain
 IPR024950  Dual specificity phosphatase
 IPR029021  Protein-tyrosine phosphatase-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000188 inactivation of MAPK activity IEA
 biological_processGO:0002819 regulation of adaptive immune response IEA
 biological_processGO:0006470 protein dephosphorylation IEA
 biological_processGO:0010633 negative regulation of epithelial cell migration IEA
 biological_processGO:0016311 dephosphorylation IEA
 biological_processGO:0032496 response to lipopolysaccharide IEA
 biological_processGO:0032873 negative regulation of stress-activated MAPK cascade IEA
 biological_processGO:0035970 peptidyl-threonine dephosphorylation IEA
 biological_processGO:0043508 negative regulation of JUN kinase activity IEA
 biological_processGO:0044387 negative regulation of protein kinase activity by regulation of protein phosphorylation IEA
 biological_processGO:0045088 regulation of innate immune response IEA
 biological_processGO:0045591 positive regulation of regulatory T cell differentiation IEA
 biological_processGO:0046329 negative regulation of JNK cascade IEA
 biological_processGO:0048709 oligodendrocyte differentiation IEA
 biological_processGO:0050680 negative regulation of epithelial cell proliferation IEA
 biological_processGO:0060266 negative regulation of respiratory burst involved in inflammatory response IEA
 biological_processGO:0070373 negative regulation of ERK1 and ERK2 cascade IEA
 biological_processGO:0090335 regulation of brown fat cell differentiation IEA
 biological_processGO:1903753 negative regulation of p38MAPK cascade IEA
 biological_processGO:1905042 negative regulation of epithelium regeneration IEA
 biological_processGO:1990264 peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0016607 nuclear speck IEA
 molecular_functionGO:0004725 protein tyrosine phosphatase activity IEA
 molecular_functionGO:0008138 protein tyrosine/serine/threonine phosphatase activity IEA
 molecular_functionGO:0008330 protein tyrosine/threonine phosphatase activity IEA
 molecular_functionGO:0008432 JUN kinase binding IEA
 molecular_functionGO:0016791 phosphatase activity IEA
 molecular_functionGO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity IEA
 molecular_functionGO:0033549 MAP kinase phosphatase activity IEA
 molecular_functionGO:0048273 mitogen-activated protein kinase p38 binding IEA


Pathways (from Reactome)
Pathway description
RAF-independent MAPK1/3 activation
Negative regulation of MAPK pathway


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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