ENSDARG00000110581


Danio rerio

Features
Gene ID: ENSDARG00000110581
  
Biological name :mapk4
  
Synonyms : mapk4 / mitogen-activated protein kinase 4
  
Possible biological names infered from orthology : P31152 / Q6P5G0
  
Species: Danio rerio
  
Chr. number: 8
Strand: 1
Band:
Gene start: 29742237
Gene end: 29769157
  
Corresponding Affymetrix probe sets: Dr.9049.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000011941
Ensembl peptide - ENSDARP00000115527
Ensembl peptide - ENSDARP00000144829
NCBI entrez gene - 406782     See in Manteia.
swissprot - B0V360
swissprot - B0V361
ZFIN ID - ZDB-GENE-040426-2835
Ensembl - ENSDARG00000110581
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 MAPK4ENSG00000141639Homo sapiens
 Mapk4ENSMUSG00000024558Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
mapk6 / mitogen-activated protein kinase 6 / Q16659* / Q61532*ENSDARG0000003210344
mapk7 / mitogen-activated protein kinase 7 / Q13164* / Q9WVS8*ENSDARG0000002311022
mapk3 / mitogen-activated protein kinase 3 / P27361* / Q63844*ENSDARG0000007057321
mapk1 / mitogen-activated protein kinase 1 / P28482* / P63085* / Mus musculus mitogen-activated protein kinase 1 (Mapk1), transcript variant 3, mRNA.*ENSDARG0000002755221
nlk2 / nemo-like kinase, type 2 / NLK* / O54949* / Q9UBE8* / nemo like kinase* / Serine/threonine-protein kinase NLK *ENSDARG0000002879318
mapk15 / mitogen-activated protein kinase 15 / Q80Y86* / Q8TD08*ENSDARG0000010082218
nlk1 / nemo-like kinase, type 1ENSDARG0000000656616


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR008271  Serine/threonine-protein kinase, active site
 IPR008350  Mitogen-activated protein (MAP) kinase, ERK3/4
 IPR011009  Protein kinase-like domain superfamily
 IPR017441  Protein kinase, ATP binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000165 MAPK cascade IEA
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0010468 regulation of gene expression IBA
 biological_processGO:0071310 cellular response to organic substance IBA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005737 cytoplasm IBA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IEA
 molecular_functionGO:0004707 MAP kinase activity IBA
 molecular_functionGO:0005524 ATP binding IEA


Pathways (from Reactome)
Pathway description
MAPK6/MAPK4 signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000028082 mapkapk5 / mitogen-activated protein kinase-activated protein kinase 5 / Q8IW41*  / complex / reaction






 

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