ENSDARG00000023110


Danio rerio

Features
Gene ID: ENSDARG00000023110
  
Biological name :mapk7
  
Synonyms : mapk7 / mitogen-activated protein kinase 7
  
Possible biological names infered from orthology : Q13164 / Q9WVS8
  
Species: Danio rerio
  
Chr. number: 12
Strand: 1
Band:
Gene start: 4220353
Gene end: 4238827
  
Corresponding Affymetrix probe sets: Dr.4939.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000119429
Ensembl peptide - ENSDARP00000042276
Ensembl peptide - ENSDARP00000117704
NCBI entrez gene - 541323     See in Manteia.
RefSeq - NM_001013451
RefSeq - XM_005156002
RefSeq Peptide - NP_001013469
swissprot - Q0H1F4
swissprot - E9QEY0
ZFIN ID - ZDB-GENE-050320-10
Ensembl - ENSDARG00000023110
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 MAPK7ENSG00000166484Homo sapiens
 Mapk7ENSMUSG00000001034Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
mapk3 / mitogen-activated protein kinase 3 / P27361* / Q63844*ENSDARG0000007057317
mapk1 / mitogen-activated protein kinase 1 / P28482* / P63085* / Mus musculus mitogen-activated protein kinase 1 (Mapk1), transcript variant 3, mRNA.*ENSDARG0000002755216
nlk2 / nemo-like kinase, type 2 / NLK* / O54949* / Q9UBE8* / nemo like kinase* / Serine/threonine-protein kinase NLK *ENSDARG0000002879316
mapk6 / mitogen-activated protein kinase 6 / Q16659* / Q61532*ENSDARG0000003210315
nlk1 / nemo-like kinase, type 1ENSDARG0000000656614
mapk4 / mitogen-activated protein kinase 4 / P31152* / Q6P5G0*ENSDARG0000011058114
mapk15 / mitogen-activated protein kinase 15 / Q80Y86* / Q8TD08*ENSDARG0000010082214


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR003527  Mitogen-activated protein (MAP) kinase, conserved site
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR017441  Protein kinase, ATP binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000165 MAPK cascade IEA
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0010468 regulation of gene expression IBA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0071310 cellular response to organic substance IBA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005737 cytoplasm IBA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IEA
 molecular_functionGO:0004707 MAP kinase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA


Pathways (from Reactome)
Pathway description
ERK/MAPK targets
Signalling to ERK5
ERKs are inactivated
Senescence-Associated Secretory Phenotype (SASP)
Gastrin-CREB signalling pathway via PKC and MAPK
RET signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000028469 rps6ka2 / ribosomal protein S6 kinase, polypeptide 2 / Q15349* / ribosomal protein S6 kinase A2*  / reaction
 ENSDARG00000060130 dusp3b / dual specificity phosphatase 3b / DUSP3* / Q9D7X3* / P51452* / dual specificity phosphatase 3* / Dual specificity protein phosphatase 3 *  / reaction
 ENSDARG00000044688 dusp4 / dual specificity phosphatase 4 / Q13115* / Q8BFV3* / Dual specificity protein phosphatase 4 *  / reaction
 ENSDARG00000061255 dusp3a / dual specificity phosphatase 3a / DUSP3* / Q9D7X3* / P51452* / dual specificity phosphatase 3* / Dual specificity protein phosphatase 3 *  / reaction
 ENSDARG00000070914 dusp6 / dual specificity phosphatase 6 / Q16828* / Q9DBB1* / Dual specificity protein phosphatase 6 *  / reaction
 ENSDARG00000101413 dusp7 / dual specificity phosphatase 7 / Q16829*  / reaction






 

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