ENSG00000006327


Homo sapiens

Features
Gene ID: ENSG00000006327
  
Biological name :TNFRSF12A
  
Synonyms : Q9NP84 / TNF receptor superfamily member 12A / TNFRSF12A
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 16
Strand: 1
Band: p13.3
Gene start: 3018445
Gene end: 3022383
  
Corresponding Affymetrix probe sets: 218368_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000460610
Ensembl peptide - ENSP00000461756
Ensembl peptide - ENSP00000326737
Ensembl peptide - ENSP00000343894
Ensembl peptide - ENSP00000458305
Ensembl peptide - ENSP00000458898
NCBI entrez gene - 51330     See in Manteia.
OMIM - 605914
RefSeq - NM_016639
RefSeq Peptide - NP_057723
swissprot - I3L3P4
swissprot - I3L539
swissprot - Q9NP84
swissprot - I3L0S4
swissprot - I3L1J9
Ensembl - ENSG00000006327
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Q9CR75ENSMUSG00000023905Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR022316  Tumour necrosis factor receptor 12


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001525 angiogenesis IEA
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0006931 substrate-dependent cell migration, cell attachment to substrate IEA
 biological_processGO:0007155 cell adhesion IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0033209 tumor necrosis factor-mediated signaling pathway TAS
 biological_processGO:0043065 positive regulation of apoptotic process IDA
 biological_processGO:0045765 regulation of angiogenesis IEA
 biological_processGO:0045773 positive regulation of axon extension IEA
 biological_processGO:0061041 regulation of wound healing IDA
 biological_processGO:0097191 extrinsic apoptotic signaling pathway IEA
 biological_processGO:2001238 positive regulation of extrinsic apoptotic signaling pathway IMP
 cellular_componentGO:0001726 ruffle IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0009986 cell surface IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
TNFR2 non-canonical NF-kB pathway
TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000239697 O43508 / TNFSF12 / TNF superfamily member 12  / reaction / complex
 ENSG00000006327 Q9NP84 / TNFRSF12A / TNF receptor superfamily member 12A  / complex / reaction
 ENSG00000127191 TRAF2 / Q12933 / TNF receptor associated factor 2  / complex / reaction
 ENSG00000006062 Q99558 / MAP3K14 / mitogen-activated protein kinase kinase kinase 14  / complex / reaction
 ENSG00000131323 TRAF3 / Q13114 / TNF receptor associated factor 3  / complex / reaction
 ENSG00000023445 BIRC3 / Q13489 / baculoviral IAP repeat containing 3  / reaction / complex
 ENSG00000110330 BIRC2 / Q13490 / baculoviral IAP repeat containing 2  / reaction / complex






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr