ENSG00000007866


Homo sapiens

Features
Gene ID: ENSG00000007866
  
Biological name :TEAD3
  
Synonyms : Q99594 / TEAD3 / TEA domain transcription factor 3
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 6
Strand: -1
Band: p21.31
Gene start: 35473597
Gene end: 35497076
  
Corresponding Affymetrix probe sets: 209454_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000384577
Ensembl peptide - ENSP00000492431
Ensembl peptide - ENSP00000416400
Ensembl peptide - ENSP00000345772
NCBI entrez gene - 7005     See in Manteia.
OMIM - 603170
RefSeq - NM_003214
RefSeq Peptide - NP_003205
swissprot - B5MCM0
swissprot - A0A1X7SBS4
swissprot - H7C4A7
swissprot - Q99594
Ensembl - ENSG00000007866
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tead3aENSDARG00000074321Danio rerio
 tead3bENSDARG00000063649Danio rerio
 TEAD3ENSGALG00000043513Gallus gallus
 Tead3ENSMUSG00000002249Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
TEAD1 / P28347 / TEA domain transcription factor 1ENSG0000018707970
TEAD4 / Q15561 / TEA domain transcription factor 4ENSG0000019790569
TEAD2 / Q15562 / TEA domain transcription factor 2ENSG0000007421963


Protein motifs (from Interpro)
Interpro ID Name
 IPR000818  TEA/ATTS domain
 IPR016361  Transcriptional enhancer factor, metazoa
 IPR027253  Transcriptional enhancer factor TEF-5 (TEAD3)


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II TAS
 biological_processGO:0006367 transcription initiation from RNA polymerase II promoter TAS
 biological_processGO:0007565 female pregnancy TAS
 biological_processGO:0035329 hippo signaling IDA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IBA
 biological_processGO:0048568 embryonic organ development IBA
 biological_processGO:0055059 asymmetric neuroblast division IGI
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005667 transcription factor complex IBA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding NAS
 molecular_functionGO:0001085 RNA polymerase II transcription factor binding IPI
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0043565 sequence-specific DNA binding IBA
 molecular_functionGO:0044212 transcription regulatory region DNA binding IBA


Pathways (from Reactome)
Pathway description
YAP1- and WWTR1 (TAZ)-stimulated gene expression
RUNX3 regulates YAP1-mediated transcription


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000018408 WWTR1 / Q9GZV5 / WW domain containing transcription regulator 1  / complex / reaction
 ENSG00000137693 YAP1 / P46937 / Yes associated protein 1  / reaction / complex






 

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