ENSG00000197905


Homo sapiens

Features
Gene ID: ENSG00000197905
  
Biological name :TEAD4
  
Synonyms : Q15561 / TEAD4 / TEA domain transcription factor 4
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 12
Strand: 1
Band: p13.33
Gene start: 2959330
Gene end: 3040673
  
Corresponding Affymetrix probe sets: 204281_at (Human Genome U133 Plus 2.0 Array)   41037_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000411475
Ensembl peptide - ENSP00000438453
Ensembl peptide - ENSP00000438960
Ensembl peptide - ENSP00000441959
Ensembl peptide - ENSP00000444528
Ensembl peptide - ENSP00000351184
Ensembl peptide - ENSP00000352926
Ensembl peptide - ENSP00000380311
NCBI entrez gene - 7004     See in Manteia.
OMIM - 601714
RefSeq - NM_201443
RefSeq - NM_003213
RefSeq - NM_201441
RefSeq Peptide - NP_958851
RefSeq Peptide - NP_958849
RefSeq Peptide - NP_003204
swissprot - Q53GI4
swissprot - A0A0A0MRF3
swissprot - H0Y7B0
swissprot - H0YFF9
swissprot - H0YFK0
swissprot - H0YG62
swissprot - H0YGS2
swissprot - Q15561
Ensembl - ENSG00000197905
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 TEAD4ENSGALG00000014342Gallus gallus
 Tead4ENSMUSG00000030353Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
TEAD1 / P28347 / TEA domain transcription factor 1ENSG0000018707973
TEAD3 / Q99594 / TEA domain transcription factor 3ENSG0000000786669
TEAD2 / Q15562 / TEA domain transcription factor 2ENSG0000007421962


Protein motifs (from Interpro)
Interpro ID Name
 IPR000818  TEA/ATTS domain
 IPR016361  Transcriptional enhancer factor, metazoa
 IPR027255  Transcriptional enhancer factor TEF-3 (TEAD4)


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001501 skeletal system development TAS
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II TAS
 biological_processGO:0006367 transcription initiation from RNA polymerase II promoter TAS
 biological_processGO:0007517 muscle organ development TAS
 biological_processGO:0035329 hippo signaling IDA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IBA
 biological_processGO:0048568 embryonic organ development IBA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005667 transcription factor complex IBA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding NAS
 molecular_functionGO:0001085 RNA polymerase II transcription factor binding IBA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0043565 sequence-specific DNA binding IBA
 molecular_functionGO:0044212 transcription regulatory region DNA binding IBA


Pathways (from Reactome)
Pathway description
YAP1- and WWTR1 (TAZ)-stimulated gene expression
RUNX3 regulates YAP1-mediated transcription


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000137693 YAP1 / P46937 / Yes associated protein 1  / reaction / complex
 ENSG00000020633 RUNX3 / Q13761 / runt related transcription factor 3  / complex / reaction
 ENSG00000018408 WWTR1 / Q9GZV5 / WW domain containing transcription regulator 1  / complex / reaction






 

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