ENSG00000008197


Homo sapiens

Features
Gene ID: ENSG00000008197
  
Biological name :TFAP2D
  
Synonyms : Q7Z6R9 / TFAP2D / transcription factor AP-2 delta
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 6
Strand: 1
Band: p12.3
Gene start: 50713828
Gene end: 50772988
  
Corresponding Affymetrix probe sets: 233987_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000008391
NCBI entrez gene - 83741     See in Manteia.
OMIM - 610161
RefSeq - NM_172238
RefSeq Peptide - NP_758438
swissprot - Q7Z6R9
Ensembl - ENSG00000008197
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Q5RJ20ENSDARG00000023272Danio rerio
 TFAP2DENSGALG00000019842Gallus gallus
 Q91ZK0ENSMUSG00000042596Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q92481 / TFAP2B / transcription factor AP-2 betaENSG0000000819648
Q6VUC0 / TFAP2E / transcription factor AP-2 epsilonENSG0000011681947
P05549 / TFAP2A / transcription factor AP-2 alphaENSG0000013720347
Q92754 / TFAP2C / transcription factor AP-2 gammaENSG0000008751044


Protein motifs (from Interpro)
Interpro ID Name
 IPR004979  Transcription factor AP-2
 IPR013854  Transcription factor AP-2, C-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0042127 regulation of cell proliferation IBA
 biological_processGO:0043524 negative regulation of neuron apoptotic process IEA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0048856 anatomical structure development IBA
 biological_processGO:0061379 inferior colliculus development IEA
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005667 transcription factor complex IEA
 molecular_functionGO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding IEA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA


Pathways (from Reactome)
Pathway description
Negative regulation of activity of TFAP2 (AP-2) family transcription factors
Activation of the TFAP2 (AP-2) family of transcription factors


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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