ENSMUSG00000042596


Mus musculus

Features
Gene ID: ENSMUSG00000042596
  
Biological name :Tfap2d
  
Synonyms : Q91ZK0 / Tfap2d / transcription factor AP-2, delta
  
Possible biological names infered from orthology : Q7Z6R9
  
Species: Mus musculus
  
Chr. number: 1
Strand: 1
Band: A3
Gene start: 19103022
Gene end: 19166346
  
Corresponding Affymetrix probe sets: 10345007 (MoGene1.0st)   1425443_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000037699
NCBI entrez gene - 226896     See in Manteia.
MGI - MGI:2153466
RefSeq - XM_006495499
RefSeq - NM_153154
RefSeq - XM_006495497
RefSeq - XM_006495498
RefSeq Peptide - NP_694794
swissprot - Q91ZK0
Ensembl - ENSMUSG00000042596
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Q5RJ20ENSDARG00000023272Danio rerio
 TFAP2DENSGALG00000019842Gallus gallus
 Q7Z6R9ENSG00000008197Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q61313 / Tfap2b / transcription factor AP-2 beta / Q92481*ENSMUSG0000002592748
Tfap2a / transcription factor AP-2, alpha / P05549*ENSMUSG0000002135948
Q6VUP9 / Tfap2e / transcription factor AP-2, epsilon / Q6VUC0*ENSMUSG0000004247747
Q61312 / Tfap2c / transcription factor AP-2, gamma / Q92754*ENSMUSG0000002864044


Protein motifs (from Interpro)
Interpro ID Name
 IPR004979  Transcription factor AP-2
 IPR013854  Transcription factor AP-2, C-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0042127 regulation of cell proliferation IBA
 biological_processGO:0043524 negative regulation of neuron apoptotic process IMP
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IDA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IDA
 biological_processGO:0061379 inferior colliculus development IMP
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005667 transcription factor complex IPI
 molecular_functionGO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding IDA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding IMP
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
Negative regulation of activity of TFAP2 (AP-2) family transcription factors
Activation of the TFAP2 (AP-2) family of transcription factors


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0006042 increased apoptosis "greater than normal programmed cell death" [RGD:Rat Genome Database submission, smb:Susan M Bello, Mouse Genome Informatics Curator]
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Allelic Composition: Sh3kbp1tm1Kuro/Sh3kbp1tm1Kuro,Cd79atm1(cre)Reth/Cd79a+,Gt(ROSA)26Sortm4(Ikbkb)Rsky/?
Genetic Background: involves: BALB/c * C57BL/6 * NZB

 MP:0009039 absent inferior colliculus "absence of the paired inferior eminence of the mesencephalic tectum" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Sh3kbp1tm1Kuro/Sh3kbp1tm1Kuro,Cd79atm1(cre)Reth/Cd79a+,Gt(ROSA)26Sortm4(Ikbkb)Rsky/?
Genetic Background: involves: BALB/c * C57BL/6 * NZB

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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