ENSG00000010219


Homo sapiens

Features
Gene ID: ENSG00000010219
  
Biological name :DYRK4
  
Synonyms : dual specificity tyrosine phosphorylation regulated kinase 4 / DYRK4 / Q9NR20
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 12
Strand: 1
Band: p13.32
Gene start: 4562204
Gene end: 4615302
  
Corresponding Affymetrix probe sets: 212954_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000441755
Ensembl peptide - ENSP00000441996
Ensembl peptide - ENSP00000444842
Ensembl peptide - ENSP00000010132
Ensembl peptide - ENSP00000438769
Ensembl peptide - ENSP00000439168
Ensembl peptide - ENSP00000439697
NCBI entrez gene - 8798     See in Manteia.
OMIM - 609181
RefSeq - NM_003845
RefSeq Peptide - NP_003836
swissprot - F5H3D3
swissprot - F5H4X6
swissprot - H0YFI4
swissprot - A0A0A0MTH5
swissprot - Q9NR20
swissprot - F5GWS4
Ensembl - ENSG00000010219
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 dyrk4ENSDARG00000070734Danio rerio
 Dyrk4ENSMUSG00000030345Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
DYRK2 / Q92630 / dual specificity tyrosine phosphorylation regulated kinase 2ENSG0000012733445
DYRK3 / O43781 / dual specificity tyrosine phosphorylation regulated kinase 3ENSG0000014347945
DYRK1B / Q9Y463 / dual specificity tyrosine phosphorylation regulated kinase 1BENSG0000010520430
HIPK2 / Q9H2X6 / homeodomain interacting protein kinase 2ENSG0000006439330
DYRK1A / Q13627 / dual specificity tyrosine phosphorylation regulated kinase 1AENSG0000015754030
HIPK1 / Q86Z02 / homeodomain interacting protein kinase 1ENSG0000016334930
HIPK3 / Q9H422 / homeodomain interacting protein kinase 3ENSG0000011042229
HIPK4 / Q8NE63 / homeodomain interacting protein kinase 4ENSG0000016039623
AC005832.4ENSG000002729219


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR017441  Protein kinase, ATP binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0018108 peptidyl-tyrosine phosphorylation IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IDA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IEA
 molecular_functionGO:0004712 protein serine/threonine/tyrosine kinase activity IEA
 molecular_functionGO:0004713 protein tyrosine kinase activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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