ENSG00000110422


Homo sapiens

Features
Gene ID: ENSG00000110422
  
Biological name :HIPK3
  
Synonyms : HIPK3 / homeodomain interacting protein kinase 3 / Q9H422
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 11
Strand: 1
Band: p13
Gene start: 33256672
Gene end: 33357023
  
Corresponding Affymetrix probe sets: 207764_s_at (Human Genome U133 Plus 2.0 Array)   210148_at (Human Genome U133 Plus 2.0 Array)   213697_at (Human Genome U133 Plus 2.0 Array)   226297_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000304226
Ensembl peptide - ENSP00000398241
Ensembl peptide - ENSP00000431710
Ensembl peptide - ENSP00000433594
Ensembl peptide - ENSP00000368301
NCBI entrez gene - 10114     See in Manteia.
OMIM - 604424
RefSeq - XM_017017077
RefSeq - NM_001048200
RefSeq - NM_001278162
RefSeq - NM_001278163
RefSeq - NM_005734
RefSeq - XM_005252729
RefSeq - XM_017017076
RefSeq Peptide - NP_001265092
RefSeq Peptide - NP_005725
RefSeq Peptide - NP_001041665
RefSeq Peptide - NP_001265091
swissprot - Q9H422
swissprot - E9PKD7
Ensembl - ENSG00000110422
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 hipk3aENSDARG00000062469Danio rerio
 hipk3bENSDARG00000062082Danio rerio
 HIPK3ENSGALG00000011695Gallus gallus
 Hipk3ENSMUSG00000027177Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
HIPK2 / Q9H2X6 / homeodomain interacting protein kinase 2ENSG0000006439352
HIPK1 / Q86Z02 / homeodomain interacting protein kinase 1ENSG0000016334948
HIPK4 / Q8NE63 / homeodomain interacting protein kinase 4ENSG0000016039618
DYRK1A / Q13627 / dual specificity tyrosine phosphorylation regulated kinase 1AENSG0000015754016
DYRK1B / Q9Y463 / dual specificity tyrosine phosphorylation regulated kinase 1BENSG0000010520414
DYRK2 / Q92630 / dual specificity tyrosine phosphorylation regulated kinase 2ENSG0000012733413
DYRK4 / Q9NR20 / dual specificity tyrosine phosphorylation regulated kinase 4ENSG0000001021912
DYRK3 / O43781 / dual specificity tyrosine phosphorylation regulated kinase 3ENSG0000014347912
AC005832.4ENSG000002729212


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR017441  Protein kinase, ATP binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006468 protein phosphorylation IDA
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0009299 mRNA transcription IDA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0018105 peptidyl-serine phosphorylation ISS
 biological_processGO:0018107 peptidyl-threonine phosphorylation ISS
 biological_processGO:0043066 negative regulation of apoptotic process IMP
 biological_processGO:0043508 negative regulation of JUN kinase activity ISS
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0016604 nuclear body IDA
 cellular_componentGO:0016605 PML body IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity TAS
 molecular_functionGO:0004674 protein serine/threonine kinase activity IDA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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