ENSG00000064270


Homo sapiens

Features
Gene ID: ENSG00000064270
  
Biological name :ATP2C2
  
Synonyms : ATP2C2 / ATPase secretory pathway Ca2+ transporting 2 / O75185
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 16
Strand: 1
Band: q24.1
Gene start: 84368527
Gene end: 84464187
  
Corresponding Affymetrix probe sets: 206043_s_at (Human Genome U133 Plus 2.0 Array)   214798_at (Human Genome U133 Plus 2.0 Array)   236171_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000456595
Ensembl peptide - ENSP00000262429
Ensembl peptide - ENSP00000397925
NCBI entrez gene - 9914     See in Manteia.
OMIM - 613082
RefSeq - XM_011523486
RefSeq - NM_001286527
RefSeq - NM_001291454
RefSeq - NM_014861
RefSeq Peptide - NP_001273456
RefSeq Peptide - NP_001278383
RefSeq Peptide - NP_055676
swissprot - A0A0A0MSP0
swissprot - H3BS90
swissprot - O75185
Ensembl - ENSG00000064270
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ATP2C2ENSGALG00000035743Gallus gallus
 A7L9Z8ENSMUSG00000034112Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ATP2C1 / P98194 / ATPase secretory pathway Ca2+ transporting 1ENSG0000001726062
ATP2A2 / P16615 / ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2ENSG0000017443732
ATP2A1 / O14983 / ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1ENSG0000019629632
ATP2A3 / Q93084 / ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3ENSG0000007437032
ATP1A3 / P13637 / ATPase Na+/K+ transporting subunit alpha 3ENSG0000010540929
ATP1A2 / P50993 / ATPase Na+/K+ transporting subunit alpha 2ENSG0000001862529
ATP1A4 / Q13733 / ATPase Na+/K+ transporting subunit alpha 4ENSG0000013268128
AC010616.2ENSG0000028550528
ATP1A1 / P05023 / ATPase Na+/K+ transporting subunit alpha 1ENSG0000016339928
ATP4A / P20648 / ATPase H+/K+ transporting alpha subunitENSG0000010567528
ATP12A / P54707 / ATPase H+/K+ transporting non-gastric alpha2 subunitENSG0000007567327


Protein motifs (from Interpro)
Interpro ID Name
 IPR001757  P-type ATPase
 IPR004014  Cation-transporting P-type ATPase, N-terminal
 IPR006068  Cation-transporting P-type ATPase, C-terminal
 IPR006413  P-type ATPase, subfamily IIA, PMR1-type
 IPR008250  P-type ATPase, A domain superfamily
 IPR018303  P-type ATPase, phosphorylation site
 IPR023298  P-type ATPase, transmembrane domain superfamily
 IPR023299  P-type ATPase, cytoplasmic domain N
 IPR030334  Calcium-transporting ATPase type 2C member 2
 IPR036412  HAD-like superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006816 calcium ion transport IEA
 biological_processGO:0034220 ion transmembrane transport TAS
 biological_processGO:0061180 mammary gland epithelium development IEA
 biological_processGO:0070588 calcium ion transmembrane transport IEA
 biological_processGO:0072659 protein localization to plasma membrane IEA
 biological_processGO:0090280 positive regulation of calcium ion import IEA
 biological_processGO:0099132 ATP hydrolysis coupled cation transmembrane transport IEA
 cellular_componentGO:0000139 Golgi membrane TAS
 cellular_componentGO:0009898 cytoplasmic side of plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0005388 calcium-transporting ATPase activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Ion transport by P-type ATPases


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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