ENSG00000066933


Homo sapiens

Features
Gene ID: ENSG00000066933
  
Biological name :MYO9A
  
Synonyms : B2RTY4 / MYO9A / myosin IXA
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 15
Strand: -1
Band: q23
Gene start: 71822289
Gene end: 72118577
  
Corresponding Affymetrix probe sets: 219027_s_at (Human Genome U133 Plus 2.0 Array)   226203_at (Human Genome U133 Plus 2.0 Array)   242512_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000457407
Ensembl peptide - ENSP00000457235
Ensembl peptide - ENSP00000457945
Ensembl peptide - ENSP00000348349
Ensembl peptide - ENSP00000398250
Ensembl peptide - ENSP00000399162
Ensembl peptide - ENSP00000454446
Ensembl peptide - ENSP00000454517
Ensembl peptide - ENSP00000455150
Ensembl peptide - ENSP00000456192
Ensembl peptide - ENSP00000456882
NCBI entrez gene - 4649     See in Manteia.
OMIM - 604875
RefSeq - XM_017022230
RefSeq - XM_011521616
RefSeq - XM_011521617
RefSeq - XM_011521618
RefSeq - XM_011521619
RefSeq - XM_011521620
RefSeq - XM_011521621
RefSeq - XM_011521622
RefSeq - XM_011521623
RefSeq - XM_017022228
RefSeq - XM_017022229
RefSeq - NM_006901
RefSeq - XM_006720539
RefSeq - XM_011521613
RefSeq - XM_011521614
RefSeq - XM_011521615
RefSeq Peptide - NP_008832
swissprot - H3BMS3
swissprot - H3BP49
swissprot - H3BRD5
swissprot - H3BSU8
swissprot - H3BMM1
swissprot - H3BU05
swissprot - H3BV44
swissprot - B2RTY4
swissprot - H3BTL9
Ensembl - ENSG00000066933
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 myo9aaENSDARG00000076729Danio rerio
 myo9abENSDARG00000073843Danio rerio
 MYO9AENSGALG00000033618Gallus gallus
 Myo9aENSMUSG00000039585Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
MYO9B / Q13459 / myosin IXBENSG0000009933137
MYO7A / Q13402 / myosin VIIAENSG0000013747419
MYO7B / Q6PIF6 / myosin VIIBENSG0000016999419
MYO10 / Q9HD67 / myosin XENSG0000014555518
MYO5A / Q9Y4I1 / myosin VAENSG0000019753517
MYO5B / Q9ULV0 / myosin VBENSG0000016730617
MYO5C / Q9NQX4 / myosin VCENSG0000012883316
MYO6 / Q9UM54 / myosin VIENSG0000019658613
AC090227.1ENSG000002669971


Protein motifs (from Interpro)
Interpro ID Name
 IPR000048  IQ motif, EF-hand binding site
 IPR000159  Ras-associating (RA) domain
 IPR000198  Rho GTPase-activating protein domain
 IPR001609  Myosin head, motor domain
 IPR002219  Protein kinase C-like, phorbol ester/diacylglycerol-binding domain
 IPR008936  Rho GTPase activation protein
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR028558  Unconventional myosin-IXa
 IPR029071  Ubiquitin-like domain superfamily
 IPR036023  Class IX myosin, motor domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007018 microtubule-based movement IEA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007601 visual perception TAS
 biological_processGO:0034329 cell junction assembly IMP
 biological_processGO:0035556 intracellular signal transduction IEA
 biological_processGO:0043547 positive regulation of GTPase activity IEA
 biological_processGO:0045198 establishment of epithelial cell apical/basal polarity IMP
 biological_processGO:0051056 regulation of small GTPase mediated signal transduction TAS
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0016459 myosin complex IEA
 cellular_componentGO:0016461 unconventional myosin complex NAS
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003774 motor activity IEA
 molecular_functionGO:0003777 microtubule motor activity IEA
 molecular_functionGO:0003779 actin binding IEA
 molecular_functionGO:0005096 GTPase activator activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0008017 microtubule binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Rho GTPase cycle


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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