ENSG00000169994


Homo sapiens

Features
Gene ID: ENSG00000169994
  
Biological name :MYO7B
  
Synonyms : MYO7B / myosin VIIB / Q6PIF6
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 2
Strand: 1
Band: q14.3
Gene start: 127535802
Gene end: 127637729
  
Corresponding Affymetrix probe sets: 216660_at (Human Genome U133 Plus 2.0 Array)   216662_at (Human Genome U133 Plus 2.0 Array)   235383_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000386850
Ensembl peptide - ENSP00000456661
Ensembl peptide - ENSP00000415090
Ensembl peptide - ENSP00000404927
Ensembl peptide - ENSP00000386461
NCBI entrez gene - 4648     See in Manteia.
OMIM - 606541
RefSeq - XM_006712539
RefSeq - XM_017004169
RefSeq - XM_011511218
RefSeq - NM_001080527
RefSeq Peptide - NP_001073996
swissprot - Q6PIF6
swissprot - C9JC21
swissprot - H3BSD9
swissprot - B9A063
Ensembl - ENSG00000169994
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 myo7bbENSDARG00000077201Danio rerio
 si:ch73-194h10.2ENSDARG00000044441Danio rerio
 MYO7BENSGALG00000001936Gallus gallus
 Myo7bENSMUSG00000024388Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
MYO7A / Q13402 / myosin VIIAENSG0000013747455
MYO10 / Q9HD67 / myosin XENSG0000014555526
MYO9A / B2RTY4 / myosin IXAENSG0000006693323
MYO5A / Q9Y4I1 / myosin VAENSG0000019753522
MYO5C / Q9NQX4 / myosin VCENSG0000012883321
MYO9B / Q13459 / myosin IXBENSG0000009933121
MYO5B / Q9ULV0 / myosin VBENSG0000016730621
MYO6 / Q9UM54 / myosin VIENSG0000019658616
AC090227.1ENSG000002669972


Protein motifs (from Interpro)
Interpro ID Name
 IPR000048  IQ motif, EF-hand binding site
 IPR000299  FERM domain
 IPR000857  MyTH4 domain
 IPR001452  SH3 domain
 IPR001609  Myosin head, motor domain
 IPR011993  PH-like domain superfamily
 IPR014352  FERM/acyl-CoA-binding protein superfamily
 IPR019748  FERM central domain
 IPR019749  Band 4.1 domain
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR029071  Ubiquitin-like domain superfamily
 IPR035963  FERM superfamily, second domain
 IPR036028  SH3-like domain superfamily
 IPR036106  Class VII myosin, motor domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007018 microtubule-based movement IEA
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:1904970 brush border assembly IPI
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005902 microvillus IEA
 cellular_componentGO:0005903 brush border IEA
 cellular_componentGO:0016459 myosin complex IEA
 cellular_componentGO:0042995 cell projection IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 cellular_componentGO:0090651 apical cytoplasm IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003774 motor activity IEA
 molecular_functionGO:0003777 microtubule motor activity IEA
 molecular_functionGO:0003779 actin binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0008017 microtubule binding IEA
 molecular_functionGO:0051015 actin filament binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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