Homo sapiens

Gene ID: ENSG00000075945
Biological name :KIFAP3
Synonyms : KIFAP3 / kinesin associated protein 3 / Q92845
Possible biological names infered from orthology :
Species: Homo sapiens
Chr. number: 1
Strand: -1
Band: q24.2
Gene start: 169921326
Gene end: 170085208
Corresponding Affymetrix probe sets: 203333_at (Human Genome U133 Plus 2.0 Array)   
Cross references: Ensembl peptide - ENSP00000354560
Ensembl peptide - ENSP00000356739
Ensembl peptide - ENSP00000356741
Ensembl peptide - ENSP00000444622
NCBI entrez gene - 22920     See in Manteia.
OMIM - 601836
RefSeq - XM_011509307
RefSeq - NM_001204514
RefSeq - NM_001204516
RefSeq - NM_001204517
RefSeq - NM_014970
RefSeq - XM_005244970
RefSeq Peptide - NP_001191446
RefSeq Peptide - NP_055785
RefSeq Peptide - NP_001191443
RefSeq Peptide - NP_001191445
swissprot - Q92845
Ensembl - ENSG00000075945
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed

Ortholog prediction (from Ensembl)
Ortholog nameID Species
 kifap3aENSDARG00000008639Danio rerio
 kifap3bENSDARG00000006862Danio rerio
 KIFAP3ENSGALG00000021047Gallus gallus
 Kifap3ENSMUSG00000026585Mus musculus

Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match

Protein motifs (from Interpro)
Interpro ID Name
 IPR000225  Armadillo
 IPR008658  Kinesin-associated protein 3
 IPR011989  Armadillo-like helical
 IPR016024  Armadillo-type fold

Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006890 retrograde vesicle-mediated transport, Golgi to ER TAS
 biological_processGO:0007017 microtubule-based process ISS
 biological_processGO:0007018 microtubule-based movement TAS
 biological_processGO:0007165 signal transduction TAS
 biological_processGO:0008104 protein localization IEA
 biological_processGO:0008285 negative regulation of cell proliferation IEA
 biological_processGO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II TAS
 biological_processGO:0035735 intraciliary transport involved in cilium assembly TAS
 biological_processGO:0043066 negative regulation of apoptotic process IEA
 biological_processGO:0046587 positive regulation of calcium-dependent cell-cell adhesion IEA
 biological_processGO:0065003 protein-containing complex assembly TAS
 biological_processGO:0072383 plus-end-directed vesicle transport along microtubule TAS
 cellular_componentGO:0000794 condensed nuclear chromosome IDA
 cellular_componentGO:0005783 endoplasmic reticulum TAS
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005813 centrosome IDA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005871 kinesin complex IEA
 cellular_componentGO:0005876 spindle microtubule IDA
 cellular_componentGO:0005929 cilium TAS
 cellular_componentGO:0005930 axoneme IEA
 cellular_componentGO:0015630 microtubule cytoskeleton IDA
 cellular_componentGO:0016939 kinesin II complex ISS
 cellular_componentGO:0030990 intraciliary transport particle IEA
 cellular_componentGO:0032391 photoreceptor connecting cilium IEA
 cellular_componentGO:0036064 ciliary basal body IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 cellular_componentGO:0097542 ciliary tip TAS
 cellular_componentGO:1990075 periciliary membrane compartment IEA
 molecular_functionGO:0005488 binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0019894 kinesin binding IPI

Pathways (from Reactome)
Pathway description
Translocation of SLC2A4 (GLUT4) to the plasma membrane
MHC class II antigen presentation
Intraflagellar transport
COPI-dependent Golgi-to-ER retrograde traffic

Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match

Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000084731 KIF3C / O14782 / kinesin family member 3C  / reaction / complex
 ENSG00000109083 IFT20 / Q8IY31 / intraflagellar transport 20  / complex / reaction
 ENSG00000168118 RAB4A / P20338 / RAB4A, member RAS oncogene family  / reaction / complex
 ENSG00000131437 KIF3A / Q9Y496 / kinesin family member 3A  / reaction / complex
 ENSG00000101350 KIF3B / O15066 / kinesin family member 3B  / complex / reaction


0 s.

External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


© Olivier Tassy / Olivier Pourquie 2007-2021
contact: otassy@igbmc.fr