ENSG00000075945


Homo sapiens

Features
Gene ID: ENSG00000075945
  
Biological name :KIFAP3
  
Synonyms : KIFAP3 / kinesin associated protein 3 / Q92845
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: -1
Band: q24.2
Gene start: 169921326
Gene end: 170085208
  
Corresponding Affymetrix probe sets: 203333_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000354560
Ensembl peptide - ENSP00000356739
Ensembl peptide - ENSP00000356741
Ensembl peptide - ENSP00000444622
NCBI entrez gene - 22920     See in Manteia.
OMIM - 601836
RefSeq - XM_011509307
RefSeq - NM_001204514
RefSeq - NM_001204516
RefSeq - NM_001204517
RefSeq - NM_014970
RefSeq - XM_005244970
RefSeq Peptide - NP_001191446
RefSeq Peptide - NP_055785
RefSeq Peptide - NP_001191443
RefSeq Peptide - NP_001191445
swissprot - Q92845
Ensembl - ENSG00000075945
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 kifap3aENSDARG00000008639Danio rerio
 kifap3bENSDARG00000006862Danio rerio
 KIFAP3ENSGALG00000021047Gallus gallus
 Kifap3ENSMUSG00000026585Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000225  Armadillo
 IPR008658  Kinesin-associated protein 3
 IPR011989  Armadillo-like helical
 IPR016024  Armadillo-type fold


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006890 retrograde vesicle-mediated transport, Golgi to ER TAS
 biological_processGO:0007017 microtubule-based process ISS
 biological_processGO:0007018 microtubule-based movement TAS
 biological_processGO:0007165 signal transduction TAS
 biological_processGO:0008104 protein localization IEA
 biological_processGO:0008285 negative regulation of cell proliferation IEA
 biological_processGO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II TAS
 biological_processGO:0035735 intraciliary transport involved in cilium assembly TAS
 biological_processGO:0043066 negative regulation of apoptotic process IEA
 biological_processGO:0046587 positive regulation of calcium-dependent cell-cell adhesion IEA
 biological_processGO:0065003 protein-containing complex assembly TAS
 biological_processGO:0072383 plus-end-directed vesicle transport along microtubule TAS
 cellular_componentGO:0000794 condensed nuclear chromosome IDA
 cellular_componentGO:0005783 endoplasmic reticulum TAS
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005813 centrosome IDA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005871 kinesin complex IEA
 cellular_componentGO:0005876 spindle microtubule IDA
 cellular_componentGO:0005929 cilium TAS
 cellular_componentGO:0005930 axoneme IEA
 cellular_componentGO:0015630 microtubule cytoskeleton IDA
 cellular_componentGO:0016939 kinesin II complex ISS
 cellular_componentGO:0030990 intraciliary transport particle IEA
 cellular_componentGO:0032391 photoreceptor connecting cilium IEA
 cellular_componentGO:0036064 ciliary basal body IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 cellular_componentGO:0097542 ciliary tip TAS
 cellular_componentGO:1990075 periciliary membrane compartment IEA
 molecular_functionGO:0005488 binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0019894 kinesin binding IPI


Pathways (from Reactome)
Pathway description
Translocation of SLC2A4 (GLUT4) to the plasma membrane
MHC class II antigen presentation
Intraflagellar transport
COPI-dependent Golgi-to-ER retrograde traffic
Kinesins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000084731 KIF3C / O14782 / kinesin family member 3C  / reaction / complex
 ENSG00000109083 IFT20 / Q8IY31 / intraflagellar transport 20  / complex / reaction
 ENSG00000168118 RAB4A / P20338 / RAB4A, member RAS oncogene family  / reaction / complex
 ENSG00000131437 KIF3A / Q9Y496 / kinesin family member 3A  / reaction / complex
 ENSG00000101350 KIF3B / O15066 / kinesin family member 3B  / complex / reaction






 

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contact: otassy@igbmc.fr