ENSG00000101350


Homo sapiens

Features
Gene ID: ENSG00000101350
  
Biological name :KIF3B
  
Synonyms : KIF3B / kinesin family member 3B / O15066
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 20
Strand: 1
Band: q11.21
Gene start: 32277664
Gene end: 32335011
  
Corresponding Affymetrix probe sets: 203943_at (Human Genome U133 Plus 2.0 Array)   225205_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000364864
NCBI entrez gene - 9371     See in Manteia.
OMIM - 603754
RefSeq - NM_004798
RefSeq Peptide - NP_004789
swissprot - O15066
Ensembl - ENSG00000101350
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 kif3bENSDARG00000101120Danio rerio
 KIF3BENSGALG00000006604Gallus gallus
 Kif3bENSMUSG00000027475Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
KIF3C / O14782 / kinesin family member 3CENSG0000008473166
KIF3A / Q9Y496 / kinesin family member 3AENSG0000013143747
KIF17 / Q9P2E2 / kinesin family member 17ENSG0000011724543
KIF11 / P52732 / kinesin family member 11ENSG0000013816031
KIF15 / Q9NS87 / kinesin family member 15ENSG0000016380829
KIF27 / Q86VH2 / kinesin family member 27ENSG0000016511529
CENPE / Q02224 / centromere protein EENSG0000013877829
KIF21B / O75037 / kinesin family member 21BENSG0000011685228
KIF5B / P33176 / kinesin family member 5BENSG0000017075928
KIF7 / Q2M1P5 / kinesin family member 7ENSG0000016681328
KIF4B / Q2VIQ3 / kinesin family member 4BENSG0000022665028
KIF5C / O60282 / kinesin family member 5CENSG0000016828028
KIF5A / Q12840 / kinesin family member 5AENSG0000015598028
KIF4A / O95239 / kinesin family member 4AENSG0000009088928
KIF21A / Q7Z4S6 / kinesin family member 21AENSG0000013911627


Protein motifs (from Interpro)
Interpro ID Name
 IPR001752  Kinesin motor domain
 IPR019821  Kinesin motor domain, conserved site
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR027640  Kinesin-like protein
 IPR036961  Kinesin motor domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006890 retrograde vesicle-mediated transport, Golgi to ER TAS
 biological_processGO:0007018 microtubule-based movement TAS
 biological_processGO:0007052 mitotic spindle organization TAS
 biological_processGO:0007100 mitotic centrosome separation TAS
 biological_processGO:0007368 determination of left/right symmetry TAS
 biological_processGO:0008089 anterograde axonal transport TAS
 biological_processGO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II TAS
 biological_processGO:0032467 positive regulation of cytokinesis IEA
 biological_processGO:0035735 intraciliary transport involved in cilium assembly TAS
 biological_processGO:0072383 plus-end-directed vesicle transport along microtubule TAS
 biological_processGO:0090307 mitotic spindle assembly IMP
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005813 centrosome IEA
 cellular_componentGO:0005819 spindle IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005873 plus-end kinesin complex TAS
 cellular_componentGO:0005874 microtubule IEA
 cellular_componentGO:0005876 spindle microtubule NAS
 cellular_componentGO:0005929 cilium TAS
 cellular_componentGO:0015630 microtubule cytoskeleton IDA
 cellular_componentGO:0016020 membrane HDA
 cellular_componentGO:0016939 kinesin II complex IDA
 cellular_componentGO:0030424 axon IEA
 cellular_componentGO:0030496 midbody IEA
 cellular_componentGO:0030990 intraciliary transport particle IEA
 cellular_componentGO:0042995 cell projection IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 cellular_componentGO:0097542 ciliary tip TAS
 cellular_componentGO:1904115 axon cytoplasm IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003777 microtubule motor activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0008017 microtubule binding IEA
 molecular_functionGO:0008574 ATP-dependent microtubule motor activity, plus-end-directed TAS
 molecular_functionGO:0017048 Rho GTPase binding IPI


Pathways (from Reactome)
Pathway description
Translocation of SLC2A4 (GLUT4) to the plasma membrane
MHC class II antigen presentation
Intraflagellar transport
COPI-dependent Golgi-to-ER retrograde traffic
Kinesins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000109083 IFT20 / Q8IY31 / intraflagellar transport 20  / reaction / complex
 ENSG00000101350 KIF3B / O15066 / kinesin family member 3B  / complex
 ENSG00000131437 KIF3A / Q9Y496 / kinesin family member 3A  / reaction / complex
 ENSG00000075945 KIFAP3 / Q92845 / kinesin associated protein 3  / reaction / complex
 ENSG00000168118 RAB4A / P20338 / RAB4A, member RAS oncogene family  / complex / reaction






 

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